Anal Canal Cancer
Conditions
Keywords
Anal Canal Cancer, brachytherapy
Brief summary
Comparative retrospective study of two anal canal brachytherapy techniques aimed at boosting \[low dose rate (LDR) and high dose rate (HDR)\]
Detailed description
Efficacy of anal canal interstitial brachytherapy evaluated by local relapse rate, Tolerance of interstitial brachytherapy of the anal canal evaluated by the rate of chronic toxicities.
Interventions
RADIATIONBrachytherapy
Brachytherapy
Sponsors
Institut Paoli-Calmettes
Study design
Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Inclusion criteria
* Patients treated by brachytherapy anal canal to boost.
Exclusion criteria
* Patients below age of 18 years
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Evaluation of the efficacy of interstitial brachytherapy of the anal canal | 1 year | Efficacy of anal canal interstitial brachytherapy evaluated by local relapse rate |
| Evaluation of the tolerance of interstitial brachytherapy of the anal canal | 1 year | Tolerance of interstitial brachytherapy of the anal canal evaluated by the rate of chronic toxicities. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Estimation of local control | 1 year | Local control defined as the time between the date of diagnosis and the date of local relapse or death or recent news |
| Estimation of disease free survival | 1 year | Disease free survival defined as the delay between the date of diagnosis and the date of local or locoregional or distant relapse or death or recent news |
| Estimation of overall survival | 1 year | Overall survival defined as the time between the date of diagnosis and the date of death or latest news |
| Comparison of the incidence of toxicities (CTCAE v4) between the 2 groups | 1 year | rate of toxicities |
Countries
France
Outcome results
None listed