Anesthetic Cost Analysis With Desflurane in Automated Gas Control Mode

Anesthetic Cost Analysis With Desflurane in Automated Gas Control Mode With Maquet Flow-i Anaesthesia Machine

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03465475

Enrollment

Registered

2018-03-14

Start date

2018-07-01

Completion date

2021-03-01

Last updated

2021-08-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Safety Issues

Keywords

Low flow anesthesia, Desflurane, Cost analysis, Automated gas control

Brief summary

Inhalation agents constitute the major part of anesthetic drug costs (20% - 25%) and a significant portion of the applied inhalation agents are thrown into the atmosphere through the waste gas system without being absorbed by the patient. The amount of waste gas is directly correlated to the fresh gas flow (FGF). Reducing the TGA during general anesthesia reduces the consumption of inhalant agents and contributes to the reduction of greenhouse gas pollution. Risks such as hypoxia, hypercapnia, inadequate depth of anesthesia and potential toxic gas accumulation were associated with low flow anesthesia, but the patient was provided with adequate safety by following pulse oximetry, capnography, FiO2 and anesthetic gas analysis. We aimed to perform anesthetic cost analysis and patient security in automated gas control mode (AGC).

Detailed description

After the ethical approvel 60 adult patients scheduled for hepatectomy will be taken to study. Patients will be monitored after they are taken to the operating room (ECG, NIBP, SpO2, Body Temp, BIS, NIRS, PVI, PI, ORI). After the anesthesia induction and tarakeal entubation, first twenty patient will take 300 mL fresh gas flow with AGC mode (group 1), Second twenty patient will take 600 mL fresh gas flow with AGC mode (group 2), third twenty patient will take 600 mL fresh gas flow with manually. Hemodynamic and gas consumption data will be recorded. An operating room will be reserved for this study.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Inclusion criteria

* Adult patients undergoing hepatectomy with general anesthesia

Exclusion criteria

* Essential data missing * Patient participating in other research projects * Drug allergy * Anesthetic complication story

Design outcomes

Primary

Measure	Time frame	Description
Amount of used anesthetic gas (desflurane)	Through study completion, an average of 2 month	Amount of used desflurane will be determined in milliliter by anesthesia machine (Maquet Flow i40) for each patient.

Secondary

Measure	Time frame	Description
Heart rate	Through study completion, an average of 2 month	Heart rate/min
Mean arterial pressure	Through study completion, an average of 2 month	Mean arterial pressure (mm/Hg)
Peripheral oxygen saturation	Through study completion, an average of 2 month	Peripheral oxygen saturation (%)

Countries

Turkey (Türkiye)

Outcome results