Best Cutoff Value of Lactate Concentration in Vaginal Fluid to Predict Time of Spontaneous Onset of Labor in PPROM

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03463811

Enrollment

Registered

2018-03-13

Start date

2018-02-15

Completion date

2018-11-30

Last updated

2018-03-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aim is to Investigate Association Between Lactate Concentration in Vaginal Fluid and Time of Spontaneous Onset of Labor in PPROM

Brief summary

The present study is aimed to assess whether lactate determination in vaginal fluid is associated with and can predict onset of labor for women with suspected preterm prelabor rupture of membranes (PPROMs).

Detailed description

Study design: Prospective observational cohort

Interventions

DIAGNOSTIC_TESTLactate concentration in vaginal fluid

Lactate concentration in vaginal fluid

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

25 Years to 35 Years

Inclusion criteria

* Age 25-35 years old * BMI 25-30 * Singleton pregnancy in presentation with a history of suspected PPROM * A live fetus with gestational age between 26+0 weeks and 34+0 weeks

Exclusion criteria

* Abruption placenta * Medical disorders and hypertensive disorders of pregnancy * Intrauterine fetal death * Known or suspected fetal anomalies * Signs of infection (Fever, increase total leucocytic count) * Multiple pregnancy. * Regular uterine contractions. * History of cervical insufficiency

Design outcomes

Primary

Measure	Time frame	Description
Time from examination to spontaneous onset of labor	48 hours	Time from examination to spontaneous onset of labor \< or \> 48 hours according to concentration of lactate in vaginal fluid

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026