Digestive or Non-digestive Neoplasia Leading to Symptomatic Duodenal Stenosis
Conditions
Keywords
duodenal stenosis, pyloric stenosis, digestive neoplasias, non-digestive neoplasias, duodenal prosthesis
Brief summary
To assess the efficacy of duodenal prostheses for duodenal stenosis established for endoscopic pyloric or duodenal stenosis on dysphagia
Detailed description
Duodenal prostheses have become, since the 2000s, the first-line treatment of unresectable duodenal tumoral stenosis. The technical success is greater than 90%, however the endoscopic revisions that are duodenal or biliary are frequent. The IPC as a center of interventional endoscopy is very often in charge of these stenoses. We wanted to evaluate the efficiency and the duration of this effectiveness in current situation. Is there still room for gastrojejunal gastrojejunal surgery or for the development of endoscopic gastrojejunal anastomoses?
Interventions
DEVICEuncovered metal duodenal prosthesis
Implantation of an uncovered metal duodenal prosthesis for symptomatic tumor stenosis
Sponsors
Institut Paoli-Calmettes
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Any symptomatic duodenal stenosis with symptomatic duodenal duodenal prosthesis between 2010 and 2017.
Exclusion criteria
* Benign stenosis or covered metallic duodenal prosthesis (usually indicated for benign disease)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Dysphagia assessment | 7 years | GOOSS = Gastric Outlet Obstruction Scoring System |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Rate of complications | 7 years | Rate of complications |
| postoperative survival | 7 years | defined as the time between the date of duodenal prosthesis insertion and the date of death or the latest news |
| Permeability duration of the duodenal stent | 7 years | defined as the time between the date of the laying of the duodenal stent and date of patient's death or RED or surgery (exceptional case) or latest news |
| Rate of duodenal endoscopic resection at 1 and 3 months postoperatively | at 1 and 3 months postoperatively | Rate of duodenal endoscopic resection at 1 and 3 months postoperatively |
| Rate of biliary endoscopic resection at 1 and 3 months postoperatively | at 1 and 3 months postoperatively | Rate of biliary endoscopic resection at 1 and 3 months postoperatively |
Countries
France
Contacts
Primary ContactFabrice CAILLOL
Backup ContactJean-Philippe RATONE
Outcome results
None listed