Solid Cancer in a Palliative Situation With Ascites
Conditions
Keywords
palliative, solid tumor, ascites
Brief summary
Current recommendations do not recommend the concomitant administration of albumin after ascites puncture in patients with ascites neoplasia unlike cirrhotic ascites. The etiology of ascites in cancer patients is multifactorial, particularly by hepatic invasion that can lead to ascites loaded with albumin. Ascites punctures therefore lead to undernutrition, recurrent early ascites by decreasing the oncotic pressure by hypo albuminemia and a state of anasarca affecting the quality of life.
Detailed description
According to the recommendations, each ascites fluid must be sent for biochemical and bacteriological analysis. Demonstrate the high gradient proportion (percent only, no threshold of significance required). The literature has already validated the importance of supplementing albumen with cirrhotic ascites. Demonstrating that some cancer patients have high gradients, this will be enough to make the practitioner think to supplement.
Interventions
DIAGNOSTIC_TESTcirrhotic albumin
Ascites puncture
DIAGNOSTIC_TESTserum albumin
blood punctures
Sponsors
Institut Paoli-Calmettes
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Inclusion criteria
* Patient over 18 years of age followed for a solid cancer in a palliative metastatic situation who had a puncture of ascites.
Exclusion criteria
* Minor patient * Known cirrhosis
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Serum-Ascites Albumin Gradient Prevalence | 3 months | Elevated Serum-Ascites Albumin Gradient Prevalence in Palliative Cancer Patients |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Metastatic sites | 3 months | Number of Metastatic sites of patients with a high gradient. |
Countries
France
Contacts
Primary ContactAurélien PROUX
Outcome results
None listed