Gingival Recession, Gingival Recession, Generalized
Conditions
Brief summary
The aim of this study was to evaluate the effect of two different treatment agents used in conjunction with subepithelial connective graft technique on root coverage outcomes in multiple recession defects. Half of patients will receive root treatment with antimicrobial photodynamic therapy and the other half will receive photobiomodulation therapy by laser on surgery site.
Detailed description
Antimicrobial photodynamic therapy has been widely used in Periodontics to obtain reduction of periodontopathogenic bacteria with absence of systemic side effects and minimal bacterial resistance. Also, it has properties of root demineralization and exposure of collagen fibers. These properties may enhance root coverage in procedures of subepithelial connective graft. Laser photobiomodulation has the potential to increase healing and repair, this can generate gains in the root coverage and dental hypersensitivity.
Interventions
PROCEDUREControl
In the procedure of subepithelial connective tissue graft, exposed dental roots will be treated by scaling and root planing only.
PROCEDUREantimicrobial photodynamic therapy
In the procedure of subepithelial connective tissue graft, exposed dental roots will be treated by antimicrobial photodynamic therapy with toluidine blue O (10mg/ml)
PROCEDUREPhotobiomodulation
After the procedure of subepithelial connective tissue graft the whole surgical site will receive red laser application.
Sponsors
University of Sao Paulo
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
* Multiple Gingival recession - two or more Miller's class I or II (2 to 5 mm of height) * Indication of root coverage by dentin hypersensitivity or esthetic. * Minimum palate thickness (1,5mm) * Visible Enamel cement junction (JCE) on the teeth to be treated and pulp vitality * Patients without signs of periodontal disease activity and with plaque index and bleeding on probing throughout ≤20%;
Exclusion criteria
* Use of drugs that affect periodontal tissues (eg: anticonvulsants, calcium channel blockers, cyclosporine, bisphosphonates, hormone-based contraceptives, steroids) * Smokers * Pregnancy * Diabetics * History of head and neck radiotherapy * Teeth with mobility * Malpositioned teeth * History of periodontal surgery at the area on the last 12 months * Patients with orthodontic therapy in progression
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Total root coverage | One year | Total root coverage measured with a periodontal probe in millimeters. Ideal if the distance from cemento-enamel junction to gingival margin = 0 mm |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Keratinized mucosa width | One year | Keratinized mucosa width is measured with a periodontal probe in mm, from gingival margin to mucogingival junction. Ideal if keratinized mucosa width \> 5mm |
| Probing depth | One year | Probing depth measured with a periodontal probe in millimeters. The distance from gingival margin and the apical point of gingival pocket or sulcus. Ideal if \<2mm. |
| Clinical attachment level | One year | Clinical attachment level measured with a periodontal probe in millimeters. The distance from cemento-enamel junction and the apical point of gingival pocket or sulcus. Ideal if \<2mm. |
| Dentin hypersensitivity | One year | Dentin hypersensitivity measured by applying an air jet on teeth and patient fills up a visual analogue scale. Ideal if = 0. |
Countries
Brazil
Outcome results
None listed