Observational, Prospective, Single-center Study: Should Body Mass Index (BMI) be Added to the Scoring Criteria of Hepatic Critically Ill Patients in Intensive Care Unit??

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03461523

Enrollment

517

Registered

2018-03-12

Start date

2018-02-10

Completion date

2021-02-19

Last updated

2021-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ICU Stay & Mortality

Brief summary

The purpose of the study is to evaluate the hypothesis of poor clinical outcomes in critically ill patients that are having abnormal BMI.

Detailed description

All demographic data will be obtained including the patients' age, sex, body mass index (BMI) & categorized into; BMI \< 18.5Kg/m2 = underweight, BMI between 18.5-24.9Kg/m2 = normal weight, while BMI between 25-29.9Kg/m2 = overweight & obese = BMI ≥ 30Kg/m2, associated co-morbidities (diabetes mellitus, hypertension, chronic renal failure, cancer& chronic liver disease), the cause of admission to ICU, Sequential Organ Failure Assessment (SOFA), nutritional risk screening (NRS) on admission & discharge, prior cardiac arrest, previous ICU admission within 6months, nosocomial infection, organ failure e.g. cardiovascular, respiratory, renal & organic support requirement e.g. hemodynamic support, mechanical ventilation, renal replacement therapy (RRT).

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Yes

Inclusion criteria

* Patients who are admitted to the intensive care unit of National Hepatology & Tropical Medicine Research Institute (NHTMRI) for medical & surgical indications during the period from February 2018 to December 2020.

Exclusion criteria

* Patients will be excluded if they have stayed in ICU ≤24 hours and underweight (BMI\<18.5).

Design outcomes

Primary

Measure	Time frame	Description
ICU stay	average 2 - 4 weeks	Length of ICU stay in days
Mortality	average 2-4 weeks	ICU Mortality in days

Secondary

Measure	Time frame	Description
the need for pharmacological support	1-4 weeks	notice & register the need for drugs to support the hemodynamics
occurrence of nosocomial infection	2-28 days	site of nosocomial infection
the need for mechanical ventilation	during ICU stay 2-4 weeks	notice & register the need for & type of mechanical ventilation; invasive or non invasive & days of ventilation
Hospital mortality	average 28 days	mortality
Hospital stay	average 2-28days	Length of hospital stay
Duration of mechanical ventilation	1-4 weeks	Duration in days

Countries

Egypt

Outcome results