Thyroid Diseases
Conditions
Keywords
IONM, thyroidectomy, bipolar probe, monopolar probe
Brief summary
Intraoperative nerve monitoring is often used in many centers during thyroidectomy. According to the investigators' knowledge, there's no study showing superiority between bipolar and monopolar stimulation probes used for nerve monitoring during thyroid surgery. In this study, the investigators aimed to compare two different types of probes and find out superiorities.Twenty-one patients who underwent primary total thyroidectomy or hemithyroidectomy were included in the study. During surgery, amplitude and latency values obtained in the same patient with both bipolar and monopolar stimulation probes from 10 different anatomical spots \[vagal nerve, recurrent laryngeal nerve inferior portion, recurrent laryngeal nerve superior portion, external branch of superior laryngeal nerve (EBSLN)\] were recorded prospectively, both when sheath was intact and after being dissected.
Interventions
DEVICEBipolar and monopolar probes (SPESS MEDICA S.r.l. Via Buccari 16153 Genova (GE), Italy) administered to all participants.
Bipolar and monopolar probes (SPESS MEDICA S.r.l. Via Buccari 16153 Genova (GE), Italy) administered to all participants.They compared each others(bipolar vs monopolar) via amplitudes and latency values.
Sponsors
Ege University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* who underwent thyroid surgery
Exclusion criteria
* Perioperative loss of electromyographic(EMG) signal (LOS) during intraoperative nerve monitorization * patients with additional pathology that may affect vocal cord function, * abnormal preoperative laryngeal examination * history of thyroid, vocal cord or other neck surgery * advanced cancer, RLN, esophageal or trachea invasion
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Comparison of amplitude values of bipolar vs. monopolar stimulation | One week | Bipolar and monopolar probes were compared regarding amplitudes(mA), at each spot and on both sides (right & left) via Wilcoxon Signed Rank Test. |
| Comparison of Latency values of bipolar vs. monopolar stimulation | One week | Bipolar and monopolar probes were compared regarding latencies(ms) , at each spot and on both sides (right & left) via Wilcoxon Signed Rank Test. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Comparison of stimulation with vs. without overlying fascia on nerve | One week | The assessment was based on the presence or absence of nerve sheaths in this group in amplitude values via Wilcoxon Signed Rank Test. |
| Comparison of stimulation pre- vs. post-resection without overlying fascia on nerve | One week | The assessment in this group was made according to pre- and post-resection amplitude values from vagus and recurrent nerve, that were compared to each other on both sides (right & left) and with both (bipolar & monopolar) probes via Wilcoxon Signed Rank Test. |
| Comparison of stimulation of inferior vs. superior parts of recurrent nerve. | One week | The assessment in this group was based on the latency values between the inferior and superior part of the recurrent nerve via Wilcoxon Signed Rank Test. |
Outcome results
None listed