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The Effect of Bariatric Surgery to Central Sensitization

Investigation of the Effect of Bariatric Surgery on Knee Pain, Disability, Quality of Life and Central Sensitization

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03460691
Enrollment
50
Registered
2018-03-09
Start date
2018-03-09
Completion date
2018-12-09
Last updated
2018-03-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bariatric Surgery, Central Sensitization

Keywords

bariatric surgery, central sensitization, knee pain, function, quality of life

Brief summary

Nowadays obesity is emerging as a very common health problem. It has been shown in various studies that obesity may be an important risk factor for the onset and progression of knee osteoarthritis (OA). The aim of this study is to determine the effects of bariatric surgery on knee pain, loss of function, quality of life and central sensitization.

Detailed description

Weight loss in patients with knee OA reduces pain and provides functional improvement. It has been shown that bariatric surgery combined with diet and exercise changes have positive effects on weight loss, knee pain and function. Neuropathic pain is a disease that affects the somatosensory system or pain that results in a lesion. It has been reported that neuropathic pain is more frequently seen in patients with high body mass index. The hyperreactivity of the central nervous system (CNS) plays an important role in the chronic pain of OA patients. It has been shown that CNS becomes hypersensitive in people with chronic OA pain and central sensitization phenomenon plays an important role in pain complaints reported by these patients. The aim of this study is to determine the effects of bariatric surgery on knee pain, loss of function, quality of life and central sensitization.

Interventions

PROCEDUREBariatric surgery

Bariatric surgery will done to the patients who were morbid obesity

Sponsors

Bursa Yuksek Ihtisas Training and Research Hospital
Lead SponsorOTHER_GOV

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No

Inclusion criteria

* Patients decided to undergo bariatric surgery * Patients with knee pain more than 3 months.

Exclusion criteria

* Patients with mental impairment, * Patients with inflammatory rheumatic disease, * Patients who had previously undergone knee surgery

Design outcomes

Primary

MeasureTime frameDescription
numeric rating scale (NRS)6 monthsIt is commonly used to measure the severity of the patients' pain. It consists of a line 10 cm. long and marked with numbers from 0 to 10. The patient is asked to mark the point corresponding to the severity of the pain on this line in the range from 0 (no pain) to 10 (most severe pain).
Western Ontario and McMaster Universities Osteoarthritis Index(WOMAC)6 monthsfor function
Nottingham Health Profile6 monthsfor quality of life
Central Sensitization Inventory (CSI)6 monthsfor central sensitization

Contacts

Primary ContactBurcu Metin Ökmen, M.D.
burcumetinokmen@gmail.com+902242955000

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026