Observational of PNH Type Cells in Korean Patients With Bone Marrow Failure Syndrome and Having Hemolytic PNH

Observational of GPI-anchored Protein-deficient (PNH-Type) Cells in Korean Patients With Bone Marrow Failure Syndrome and Having Hemolytic Paroxymal Nocturnal Hemoglobinuria (OPENK)

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03460301

Acronym

OPENK

Enrollment

233

Registered

2018-03-09

Start date

2015-03-24

Completion date

2020-08-12

Last updated

2025-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

PNH

Brief summary

Patients who are positive of PNH-type cells are followed up for the percentage of PNH-type cells regularly for examining how it change.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

19 Years to No maximum

Inclusion criteria

* Patients with Commbs' test - negative * Any patients meeting any of Idiopathic AA/MDS/Patients who had PNH clone size \<10%

Design outcomes

Primary

Measure	Time frame
Time-course changes in the percentage of PNH-type cells in patients who are positive of PNH-type cells during period	5 years

Outcome results