Cirrhosis, Sarcopenia, Malnutrition, Hernia, Abdominal
Conditions
Keywords
Cirrhosis, Sarcopenia, Malnutrition, Inguinal hernia, Umbilical hernia, Undernutrition
Brief summary
The study evaluates whether sarcopenia influences the prevalence of abdominal hernias in patients with cirrhosis.
Detailed description
Sarcopenia is a common condition in patients with cirrhosis, with a prevalence of around 50%. It is unknown if the presence of sarcopenia may influence the prevalence of abdominal hernias in this group of patients. Clinical, nutritional and radiological evaluation will be performed in two groups of cirrhotic patients to evaluate this hypothesis.
Interventions
DIAGNOSTIC_TESTComputed Tomography Scan
The results of the CT scan and the hand-grip test will be used for diagnosis of sarcopenia. The Royal Free Hospital-Global Assessment (RFH-GA) results will classify the nutritional status of the patient.
Sponsors
University of Sao Paulo
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* ≥ 18 years * Previous diagnosis of cirrhosis
Exclusion criteria
* Acutely decompensated cirrhosis * Other chronic diseases in advanced stage (e.g. cardiac failure, chronic obstructive pulmonary disease, cancer) * Cognitive impairment, delirium, non-controlled psychosis
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Prevalence of Sarcopenia | Through study completion (an average of 1 year) | Prevalence of Sarcopenia in patients with cirrhosis |
| Influence of Sarcopenia in Prevalence of Abdominal Hernias in Patients with Cirrhosis | Through study completion (an average of 1 year) | Influence of Sarcopenia in Prevalence of Abdominal Hernias in Patients with Cirrhosis |
Countries
Brazil
Outcome results
None listed