Acute Kidney Injury, Adverse Effect, Cross-sectional Study, Staphylococcal Infections, Vancomycin
Conditions
Brief summary
The objective of this study was to investigate the current situation of vancomycin (VAN)-associated acute kidney injury (VA-AKI) in China and identify the risk factors for VA-AKI, as well as to comprehensively examine the risk related to concurrent drug use. Further, the investigators assessed the outcomes of patients who developed VA-AKI and the risk factors for these outcomes. Finally, the investigators aimed to provide suggestions for improving the prevention and treatment of VA-AKI in China.
Interventions
DRUGVancomycin
Patients who have vancomycin associated acute kidney injury will be in the Van-AKI group, and those who don't have vancomycin associated acute kidney injury will be in the none VAN-AKI group.
Sponsors
Peking University First Hospital
Study design
Observational model
CASE_CROSSOVER
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Using Vancomycin * ≥18 years old
Exclusion criteria
* Medical records were incomplete * Had been diagnosed with stage 5 CKD or were regularly receiving dialysis * SCr were not being adequately monitored to detect the development of AKI * Had undergone nephrectomy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Vancomycin-associated acute kidney injury(VAN-AKI) occuration rate | 1 year |
Secondary
| Measure | Time frame |
|---|---|
| VAN-AKI detection rate | 1 year |
| TDM detction rate | 1 year |
| 0h Serum creatinine detction rate | 1 year |
| 48h Serum creatinine detction rate | 1 year |
Countries
China
Contacts
Primary ContactLingyun Ma
Outcome results
None listed