HIV/AIDS
Conditions
Brief summary
The overall aim of this R34 application is to adapt and feasibility test an evidence-based HIV prevention education for high-risk, underserved rural women in Appalachia. This study has potential to make a significant contribution to science by advancing knowledge on the use of social media to increase access to prevention interventions to reduce high-risk substance use and related health disparities among rural women during a time of emerging and significant public health risk in Appalachia. Successfully accomplishing study aims will respond to a critical and unmet need to increase access to prevention interventions using social media, as well as advance knowledge about the high-risk drug use behaviors among vulnerable populations.
Detailed description
The overall aim of this R34 application is to adapt and feasibility test an evidence-based intervention for HIV prevention for a high-risk group of rural women in Appalachia. This study has potential to make a significant contribution to science by advancing knowledge on the use of social media to increase access to prevention interventions to reduce high-risk substance use and related health disparities among rural women during a time of emerging and significant public health risk in Appalachia. Successfully accomplishing study aims will respond to a critical and unmet need to increase the reach and scope of prevention interventions using social media, as well as advance knowledge about the high-risk drug use behaviors of this underserved group. Considering the need for prevention interventions among this high-risk group and the popularity of Facebook, the purpose of this R34 proposal is to adapt an evidence-based HIV prevention intervention for social media delivery and to feasibility test through a randomized control trial with 60 high-risk rural women drug users. The following aims guide the proposed study: (1) Adapt the NIDA Standard for HIV prevention for delivery via Facebook; and (2) Examine the feasibility of the adapted intervention with high-risk rural women through a randomized control pilot. The proposed use of Facebook in this study is promising because it is a stable, widely used, cost-efficient platform that could be leveraged to increase access to critically needed HIV prevention education. This study presents an exciting opportunity to examine the use of Facebook as a technique to expand the reach of evidence-based preventions interventions for high-risk drug users who are not likely to engage in formal treatment. Findings from this study will inform development of the larger R01 which would allow examination of the effectiveness and sustainability of this HIV prevention intervention in understudied, high risk populations.
Interventions
BEHAVIORALNIDA Standard for HIV Prevention
The NIDA Standard is a manualized, HIV prevention education intervention focused on reducing risky sexual and drug use practices. It will be adapted for Facebook in this pilot trial.
Sponsors
Michele Staton
National Institute on Drug Abuse (NIDA)
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* NM-ASSIST indicators of high-risk drug use during the 6 months before jail (including injection); * engagement in at least one sexual risk behavior in the past 3 months; * no evidence of cognitive impairment (GAIN, Dennis, 1998), * no evidence of active psychosis (currently experiencing hallucinations), * no self-reported current symptoms of physical withdrawal from a recent episode of drug use; * self-reported HIV negative status; * projected jail release date within 3 months; * active Facebook user prior to entering jail (defined as having a Facebook account that was checked at least once a week); and * reside in a rural, Appalachian county prior to incarceration.
Exclusion criteria
* Not incarcerated and screened eligible based on above mentioned criteria
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Facebook Enrollment | 3 months | The number of participants who are released and accept the "friend" request from the Facebook study profile |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Number of Participants With Use of Injected Drugs | 3 months | Use of injected drugs in the last 3-months at follow-up |
Countries
United States
Contacts
PRINCIPAL_INVESTIGATORMichele Staton, PhD
University of Kentucky
Participant flow
Participants by arm
| Arm | Count |
|---|---|
| NIDA Standard Via Facebook Participants will receive the NIDA Standard via Facebook
NIDA Standard for HIV Prevention: The NIDA Standard is a manualized, HIV prevention education intervention focused on reducing risky sexual and drug use practices. It will be adapted for Facebook in this pilot trial. | 30 |
| Re-entry Services as Usual Participants will receive standard re-entry services available in the community and through the criminal justice system | 30 |
| Total | 60 |
Baseline characteristics
| Characteristic | NIDA Standard Via Facebook | Re-entry Services as Usual | Total |
|---|---|---|---|
| Age, Continuous | 34.6 years STANDARD_DEVIATION 8.6 | 38.3 years STANDARD_DEVIATION 7.3 | 36.4 years STANDARD_DEVIATION 8.1 |
| Number of Years of Education Completed | 11.6 years STANDARD_DEVIATION 2 | 12.7 years STANDARD_DEVIATION 1.9 | 12.1 years STANDARD_DEVIATION 2 |
| Race (NIH/OMB) American Indian or Alaska Native | 0 Participants | 0 Participants | 0 Participants |
| Race (NIH/OMB) Asian | 0 Participants | 0 Participants | 0 Participants |
| Race (NIH/OMB) Black or African American | 0 Participants | 0 Participants | 0 Participants |
| Race (NIH/OMB) More than one race | 0 Participants | 0 Participants | 0 Participants |
| Race (NIH/OMB) Native Hawaiian or Other Pacific Islander | 0 Participants | 0 Participants | 0 Participants |
| Race (NIH/OMB) Unknown or Not Reported | 0 Participants | 0 Participants | 0 Participants |
| Race (NIH/OMB) White | 30 Participants | 30 Participants | 60 Participants |
| Sex: Female, Male Female | 30 Participants | 30 Participants | 60 Participants |
| Sex: Female, Male Male | 0 Participants | 0 Participants | 0 Participants |
Adverse events
| Event type | EG000 affected / at risk | EG001 affected / at risk |
|---|---|---|
| deaths Total, all-cause mortality | 0 / 27 | 0 / 23 |
| other Total, other adverse events | 20 / 27 | 19 / 23 |
| serious Total, serious adverse events | 2 / 27 | 0 / 23 |
Outcome results
Primary
Facebook Enrollment
The number of participants who are released and accept the friend request from the Facebook study profile
Time frame: 3 months
Population: Number of participants released from jail, thus eligible to accept the friend request from the Facebook profile. All participants who were released were eligible to accept the friend request then individuals randomized to the NIDA Standard via Facebook were sent an additional invite to the closed intervention group
| Arm | Measure | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|
| NIDA Standard Via Facebook | Facebook Enrollment | 15 Participants |
| Re-entry Services as Usual | Facebook Enrollment | 15 Participants |
Secondary
Number of Participants With Use of Injected Drugs
Use of injected drugs in the last 3-months at follow-up
Time frame: 3 months
Population: Individuals who were released and completed the 3 month follow up
| Arm | Measure | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|
| NIDA Standard Via Facebook | Number of Participants With Use of Injected Drugs | 8 Participants |
| Re-entry Services as Usual | Number of Participants With Use of Injected Drugs | 6 Participants |