Itch; Athlete
Conditions
Keywords
whole body vibration, erythema, tryptase, unpleasantness
Brief summary
Intense itch on the legs sometimes associated with redness can be adverse effects of whole body vibration (WBV) according to own observations and numerous posts in non-professional online-blogs. To the investigators' knowledge, the appearance of itch and/or a rash during WBV exercise has not yet been described. The research objectives are: 1. To determine the effect of WBV on itch rating and its unpleasantness and on skin changes. 2. To determine the effect of WBV on immunoglobulin E (IgE) and serum tryptase
Detailed description
Objectives Intense itch on the legs sometimes associated with redness can be adverse effects of WBV according to the investigators observations and numerous posts in non-professional online-blogs. To the investigators knowledge, the appearance of itch and/or a rash during WBV exercise has not yet been described. The objectives of this study are: 1. to determine the effect of WBV on itch rating and its unpleasantness and on skin changes. 2. to determine the effect of WBV on serum tryptase. Hypothesis The working hypothesis is that repeated WBV leads to an increase of itching and erythema. Further investigators hypothesize that repeated WBV does not lead to an increase in serum tryptase. Inclusion and exclusion criteria will be evaluated. Subjects will be instructed to not shave their legs one week before the intervention day and to shave only the left leg from the ankle to the knee on the day prior to the intervention day. On the intervention day, subjects will be informed in detail about the study protocol and written informed consent will be collected. If a pregnancy cannot be excluded (days from last menstruation) subjects are instructed to do a pregnancy test. Then, a blood sample will be taken. Subsequently, subjects will be instructed to stand on the vibration plate (Galileo 900) in a slightly crouched position with their hands loosely resting on the rail. Subjects will complete ten 1-minute WBV repetitions interspaced by 1-minute breaks in seated position. During each break, subjects will rate the itch intensity, and skin changes will be captured. Sixty minutes after the last WBV repetition, another blood sample will be taken. Subjects will rest until itch and erythema return to baseline. During resting phase subjects will fill in the Eppendorf itch questionnaire and the Erlanger atopy score.
Interventions
OTHERWhole body vibration training
10 x 1 min whole body vibration exposure
Sponsors
University Hospital, Basel, Switzerland
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE
Intervention model description
The design of the study is a single-centre cross-sectional single-arm intervention study.
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 35 Years
Healthy volunteers
Yes
Inclusion criteria
* age 18-35 years * female * Informed Consent as documented by signature (Appendix Informed Consent Form)
Exclusion criteria
* itchy skin diseases * hay fever * asthma * chronic venous insufficiency * peripheral artery disease * musculoskeletal diseases or injuries affecting the legs, hips and pelvis * BMI \< 17 and \> 35 kg/m2 * pregnancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Itch intensity | 0 months | 0 to 10 numerical rating scale (NRS) (best score: 0 - no itch; worst score: 10) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Itch characteristics | 0 months | measured using Eppendorf itch questionnaire |
| Itch unpleasantness | 0 months | 0 to 10 numerical rating scale (NRS) (best score: 0 - no unpleasantness; worst score: 10) |
| Skin surface temperature | 0 months | assessed using a infrared thermal camera |
| Erlanger atopy score | 0 months | Erlanger atopy score (best score: 0 - no atopy; worst score: 100) |
| Total immunoglobulin E (IgE) concentration | 0 months | Serum |
| Tryptase concentration | 0 months | serum |
| Erythema intensity | 0 months | assessed using an erythema meter |
Countries
Switzerland
Outcome results
None listed