Evaluation of Central Compartment Dissection Without Thyroidectomy

To Evaluate the Practicable, Thoroughness and Clinical Value of Bilateral Central Compartment Dissection While Preserve Contrary Thyroid Glands

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03454464

Enrollment

100

Registered

2018-03-06

Start date

2018-01-01

Completion date

2018-12-31

Last updated

2018-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Central Compartment Neck Dissction, Thyroid Cancer, Thyroidectomy

Brief summary

In accordance with the current guidelines,papillary thyroid microcarcinoma such as turmo invasive nerve or trachea, requires total thyroidectomy for follow-up iodine-131 treatment.In the course of clinical work, if the patient can achieve R0 resection, most of the patients do not need iodine-131 treatment,Therefore, there is no need to continue total thyroidectomy.To evaluate the practicable, thoroughness and Clinical value of bilateral central compartment dissection while preserve contrary thyroid glands.

Detailed description

In accordance with the current guidelines,papillary thyroid microcarcinoma such as turmo invasive nerve or trachea, requires total thyroidectomy for follow-up iodine-131 treatment.In the course of clinical work, if the patient can achieve R0 resection, most of the patients do not need iodine-131 treatment,Therefore, there is no need to continue total thyroidectomy.This study assesses new procedures by adjusting the sequence of procedures. complications and the thoroughness of the operation were evaluated, thus Clinical value of bilateral central compartment dissection with preserve contrary thyroid glands were ananlyed.

Interventions

PROCEDUREConventional

Conventional operation ,Thyroidectomy was performed first, and central compartment dissection was performed. This is a routine procedure

PROCEDUREcentral neck dissection first

central neck dissection first ,after FNA confirmed of thyroid carcinoma, the central compartment neck dissection was carried out before thyroidectomy , finally complement of central compartment neck dissection.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 70 Years

Healthy volunteers

Inclusion criteria

Tumor diameter less than 1cm The tumor is located in the lower part of the gland No lateral cervical lymph node metastases Traditional open surgery

Exclusion criteria

Select the endoscopic surgery or robotic surgery patients Tumor invades the surrounding trachea and esophagus Patients refused to participate

Design outcomes

Primary

Measure	Time frame	Description
number of the lymph node	2 day post operation	the number of the lymph node
number of postive lymph node	2 day post operation	The number of postive lymph node
The weight of the central compartment tissue.	introoperation	The weight of the central compartment tissue.

Secondary

Measure	Time frame	Description
thyroid volume	The day before the operation	thyroid volume
recurrent laryngeal nerve palsy	1 day ,2weeks,3months,6months post operation	the number of recurrent laryngeal nerve palsy

Countries

China

Contacts

Primary Contactwen-xin zhao, md

zhaowx@fjmu.edu.cn13365910359

Backup Contactbo wang, md

wangbo@fjmu.edu.cn13705947900

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026