Long-term Intraocular Lens (IOL) Decentration and Tilt in Eyes With Pseudoexfoliation Syndrome (PES) Following Cataract Surgery

Assessment of Long-term Intraocular Lens (IOL) Decentration and Tilt in Eyes With Pseudoexfoliation Syndrome (PES) Following Cataract Surgery

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03453827

Enrollment

Registered

2018-03-05

Start date

2016-04-01

Completion date

2017-04-28

Last updated

2018-03-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cataract, Pseudoexfoliation Syndrome, Pseudophakia

Keywords

Pseudoexfoliation Syndrome, Cataract, Aberration, IOL decentration, IOL tilt

Brief summary

To evaluate long-term intraocular lens (IOL) decentration and tilt in eyes with pseudoexfoliation syndrome (PES) following cataract surgery using Visante anterior segment OCT and iTrace Visual Function Analyzer.

Detailed description

64 eyes following cataract surgery from 2009 to 2012 were included, 34 eyes had PES, 30 eyes did not show PES. A standard phacoemulsification procedure followed by IOL implantation was performed and patients were followed 4-6 years after surgery (mean=69 months). Best corrected visual acuity (BCVA), intraocular pressure (IOP) and capsulorhexis size were measured. IOL tilt and IOL decentration were evaluated using Visante Omni anterior segment OCT (Carl Zeiss Jena GmBH, Germany). The iTrace VFA (Visual Function Analyzer, Topcon Medical Systems, Inc.) was used to measure internal, corneal and total optical aberrations.

Interventions

OTHERno intervention

no intervention

Study design

Observational model

CASE_CONTROL

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 125 Years

Inclusion criteria

* patients 4-6 years after standard cataract surgery * pseudoexfoliation Syndrome (PES)

Exclusion criteria

* Diabetic retinopathy * Age related macula Degeneration * retinal bloodvessel disease

Design outcomes

Primary

Measure	Time frame	Description
IOL decentration	4-6 years after cataract surgery	decentration of IOL is measured using Hoya iTrace
IOL tilt	4-6 years after cataract surgery	tilt of implanted IOL is measured using Hoya iTace

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026