Ventricular Tachycardia
Conditions
Keywords
ablation, sudden death, signal averaged ECG, T wave alternans, heart rate variability
Brief summary
Sudden cardiac death is a frequent cause of cardiovascular mortality. Numerous rhythmic risk assessment criterion have been described targeting the substratum, the cardiac nervous tone or the trigger of arrhythmias. Development of ventricular tachycardia ablation in the past few years show interesting results preventing the recurrence of ventricular arrhythmias.
Detailed description
Sudden cardiac death is a frequent cause of cardiovascular mortality. Numerous rhythmic risk assessment criterion have been described targeting the substratum, the cardiac nervous tone or the trigger of arrhythmias. Development of ventricular tachycardia ablation in the past few years show interesting results preventing the recurrence of ventricular arrhythmias. Rhythmic risk assessment criterions have never been studied in relation with ventricular tachycardia ablation. The purpose of this study is to explore the modifications of these criterions after ventricular tachycardia ablation.
Interventions
PROCEDUREventricular tachycardia ablation
The usual organization of hospitalization of the patients addressed for ventricular tachycardia ablation and his follow-up are not modified by the protocol. .
Sponsors
University Hospital, Toulouse
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients undergoing ventricular tachycardia, * patients with ischemic cardiomyopathy according to European Society of Cardiology Guidelines, * patients with implanted cardiac defibrillator.
Exclusion criteria
* Contra-indication to stress test, * permanent atrial fibrillation, * permanent ventricular pacing, * left bundle block.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| measure assessing change before and after Ventricular Tachycardia Ablation of the non-invasive parameters analysis of the rhythmic risk before and after Ventricular Tachycardia Ablation | 10 minutes and 60 minutes after the Ventricular Tachycardia Ablation | non invasive parameters analysis of the rhythmic risk will be evaluated by the evaluation of the T wave alternans |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Assessing the correlations of the modifications of the risk criterion after ablation with the recurrences of arrhythmias at one year follow-up | 3 months, 6 months and 12 months after the Ventricular Tachycardia Ablation | the recurrences of arrhythmias will be evaluated . There will be assessed by the informations reveled by the Implantable automatic defibrillator |
| Study of the correlation between the modifications of non-invasive parameters analysis of the rhythmic risk and the success of the ablation procedure | 3 months, 6 months and 12 months after the Ventricular Tachycardia Ablation | Success of the ablation procedure is defined by the absence of inducible Ventricular Tachycardia at the end of the procedure. |
Countries
France
Contacts
Primary ContactPhilippe MAURY, MD
Backup ContactIsabelle OLIVIER, PhD
Outcome results
None listed