Soft Tissue Lesion, Soft Tissue Mass, Soft Tissue Neoplasm, Soft Tissue Sarcoma
Conditions
Keywords
US-CNB, Soft Tissue Mass, Soft Tissue Sarcoma, Soft Tissue Neoplasm, Soft Tissue Lesion
Brief summary
A retrospective evaluation of soft tissue tumors that have undergone core needle biopsy with US guidance (US-CNB)
Detailed description
The present study is designed to be the first step in the creation of an interdisciplinary platform collecting data on patients and procedures to provide a predictive tool to help physicians in the management of patients affected by a soft tissue lesion. The primary aim of our work is to evaluate the diagnostic yield of US-CNB. The secondary aim is to exploit all the imaging data conventionally available at a Sarcoma Center before a biopsy on a soft tissue mass, to build a multiparametric model and score of prediction of malignancy, and eventually of biological behavior - grading.
Interventions
None listed
Sponsors
Istituto Ortopedico Rizzoli
Study design
Observational model
OTHER
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* Patients undergone US-CNB for soft tissue lesions at the Rizzoli Orthopaedic Institute
Exclusion criteria
* Patients whose histological diagnosis is not available
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Diagnostic yield | One year | Diagnostic yield will be defined as the number of diagnostic core needle biopsies divided by the total number of core needle biopsies. A diagnostic yield \> 94% will be considered sufficient to produce a sample to reach the histological diagnosis. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Prediction of malignancy | One year | To determine which imaging features and biomarkers correlates with malignancy and biological behavior of soft tissue masses. |
Countries
Italy
Outcome results
None listed