Oesophageal Cancer
Conditions
Keywords
Thoracoabdominal surgery, Physical Therapy, Inspiratory Muscle Training, Physical Activity
Brief summary
Thoracoabdominal oesophageal resection for cancer is a procedure with high risks for complications, and patients' preoperative status is a crucial factor for outcome. There are only a few studies that evaluate the effect of preoperative intervention, including physical exercises and breathing exercises, after this type of surgery. The aim of the study is therefore to evaluate the effect of a training intervention before resection of the oesophagus. One hundred patients scheduled for oesophagus resection according to Ivor-Lewis from five different hospitals in Sweden will be included. The patients will be randomized to an intervention group or a control group. The training intervention starts directly after preoperative radiotherapy and chemotherapy are given and lasts until three months postoperatively. Intervention includes increased physical activity, strength training and respiratory muscle training. At inclusion and three months after discharge, the patients will undergo tests of physical function and lung function. In addition, they will fill in questionnaires concerning level of physical function, level of physical activity and quality of life. These questionnaires will also be answered one year after surgery.
Interventions
OTHERPretraining
Increased physical activity, and daily strength training and breathing exercises.
OTHERUsual care
Preoperative information
Sponsors
Göteborg University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Investigator)
Masking description
Assessor will not be aware of which group the patients are included in.
Intervention model description
A single blind, randomized, controlled, intervention study. Evaluation of the addition of increased physical activity and respiratory muscle training for patients undergoing thoracoabdominal esophagus resection compared to standard care
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* Patients scheduled to undergo thoracoabdominal oesophagus resection at one of the five included centra
Exclusion criteria
* \< two weeks between inclusion and surgery * benign reason for surgery * difficulties in speaking and reading Swedish * other injury or disease limiting the ability to perform the intervention.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| 6 minutes walk test | From inclusion to 3 months postoperatively | Test of physical capacity |
Other
| Measure | Time frame | Description |
|---|---|---|
| Postoperative recovery | From surgery to 1 year postoperatively | The Postoperative Recovery Profile |
| Spirometry | From inclusion to 3 months postoperatively | Vital capacity |
| Respiratory muscle strength | From inclusion to 3 months postoperatively | Maximal Inspiratory Pressure and maximal expiratory pressure |
| Hand strength | From inclusion to 3 months postoperatively | Hand strength (Jamar) |
| Leg strength- calf strength | From inclusion to 3 months postoperatively | Heel rise test |
| Physical function | From inclusion to 1 year postoperatively (The whole study period) | Disability Rating Index |
| Rib cage range of motion | From inclusion to 3 months postoperatively | Chest excursion and Respiratory Movement Measurement Instrument |
| Level of physical activity | From inclusion to 1 year postoperatively (The whole study period) | Scale by Grimby and Frändin |
| Pain in the ribcage | From inclusion to 1 year postoperatively (The whole study period) | Numeric rating scale, Scale from 0-10 where 0 indicates no pain and 10 worst imaginable pain |
| Generic Quality of life | From inclusion to 1 year postoperatively (The whole study period) | EORTC 3 modules |
| Leg strength | From inclusion to 3 months postoperatively | Chair stands test |
Countries
Sweden
Outcome results
None listed