Fetal Macrosomia
Conditions
Brief summary
Fetal macrosomia defined as birth weight above 90th centile ,macrosomia occurs in 42-62%of pregnancy complicated by type 1 diabetes mellitus ,in 30-56% of pregnancy complicated by type 2 diabetes mellitus . -The delivery of macrosomic infant has potentially severe consequence for both the newborn and mother .Increased birth weight increase the risk in the fetus of shoulder dystocia and premature brachial plexus injury ,and those infant weighing above 4500g are at increased risk for neonatal morbidity ,including the need for assisted ventilation and meconium aspiration .Maternal complication result from operative delivery and include postpartum hemorrhage ,third or fourth degree laceration and postpartum infection .
Detailed description
Estimated fetal body weight is needed especially when head measurement is impossible whenever the fetal head is positioned low in pelvic brim .A convenient method for estimating fetal body weight without head measurement was thus required . -The human placenta develop with the principal function of providing nutrients and oxygen to the fetus ,adequate fetal growth and subsequent normal birth weight depend on normal placenta .
Interventions
DIAGNOSTIC_TESTUltrasound
Ultrasound will be done to every pregnant lady
DIAGNOSTIC_TESTHbA1c level in blood
a blood sample will be taken to measure HbA1c level
Sponsors
Kasr El Aini Hospital
National Research Centre, Egypt
Aljazeera Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 43 Years
Inclusion criteria
* 1.Singleton gestational 2.Gestational age over 16-20 weeks 3.Intact membrane 4.Normal umbilical morphology (two arteries and one vein )
Exclusion criteria
1. The presence of fetal congenital anomaly . 2. Multifetal pregnancy. 3. Maternal chronic disease (hypertension, renal disease ,and pulmonary disease ,etc.) 4. Patient with a diagnosis such as oligohydramnios ,preeclampsia and intrauterine growth retardation . 5. Patient who used cigarette or alcohol during pregnancy.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| the number of paticipants who will have babies with macrosomias | within a week from delivery | To detect number of fetuses who will develop macrosomia |
Countries
Egypt
Contacts
Primary ContactMahmoud Alalfy, M.s.c
Backup ContactAhmed Elgazzar, M.D
Outcome results
None listed