Incidence and Risk Factors of Central Line Catheter Related Thrombosis

Study About the Incidence and Risk Factors of the Central Line Catheter Related Right Internal Jugular Vein Thrombosis in Pediatric Patients

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03450785

Enrollment

Registered

2018-03-01

Start date

2018-03-07

Completion date

2020-04-08

Last updated

2021-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Central Line Complication

Brief summary

Central venous catheters are frequently used for monitoring haemodynamic status and rapidly delivering fluid therapy during the peri- and postoperative periods. Indwelling central venous catheters are typically used 7-14 days postoperatively for additional monitoring and treatment, but patients may develop asymptomatic catheter-related thrombosis, leading to life-threatening pulmonary embolism and death. Early detection helps to avoid such complications. This prospective observational study investigated the risk factors associated with catheter-related right internal jugular vein thrombosis in pediatric patients. The study enrolled 80 pediatric patients who were scheduled to receive central venous catheter. To detect thrombus formation, Doppler ultrasound examinations from the thyroid cartilage level to the supraclavicular region were used after CVC placement and on each of the following days until the catheter was removed.

Interventions

OTHERultrasound examination

Doppler ultrasound examinations from the thyroid cartilage level to the supraclavicular region were used after CVC placement and on each of the following days until the catheter was removed.

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

No minimum to 6 Years

Healthy volunteers

Inclusion criteria

* pediatric patients who were scheduled to catheterize central venous catheter

Exclusion criteria

* patients who had skin infections on the right side of the neck, making them unsuitable for placement of the catheter via the right side of the neck * patients who had blood coagulation lesions or bleeding tendencies * patients with thrombocytopenia * patients with a history of right internal jugular vein thrombosis * patients who presented right internal jugular vein thrombosis or stenosis on preoperative Doppler ultrasound examination

Design outcomes

Primary

Measure	Time frame
thrombus formation using doppler ultrasound examination of internal jugular vein	after central venous catheter placement and on each of the following days until the catheter was removed (maximum 5 days)

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026