Parasympathetic Cardiovascular Function Disorder
Conditions
Keywords
heart rate variability, intraarterial chemotherapy, ophthalmic arterial chemotherapy
Brief summary
A patient undergoing ophthalmic arterial chemosurgery may experience a sudden, profound decrease in lung compliance when the microcatheter is in the ICA or ophthalmic artery. However, underlying pathophysiology of the respiratory complication is unknown. In this study, the investigators are going to investigate the relation between underlying balance of parasympathetic and sympathetic tone and the respiratory complications by analyzing heart rate beat-to-beat variability.
Detailed description
A patient undergoing ophthalmic arterial chemosurgery may experience a sudden, profound decrease in lung compliance when the microcatheter is in the ICA or ophthalmic artery. However, underlying pathophysiology of the respiratory complication is unknown. In this study, the investigators are going to investigate the relation between underlying balance of parasympathetic and sympathetic tone and the respiratory complications by analyzing heart rate beat-to-beat variability. Also, the investigators are going to investigate whether baseline heart rate variability can predict respiratory complications during the procedures.
Interventions
None listed
Sponsors
Seoul National University Hospital
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
No minimum to 20 Years
Healthy volunteers
No
Inclusion criteria
* Patients undergoing ophthalmic arterial chemotherapy
Exclusion criteria
* None
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Heart rate variability | 5 min after microcatheter enters ophthalmic artery | Heart rate variability |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Heart rate variability | 5 min after anesthesia induction | Heart rate variability |
Countries
South Korea
Outcome results
None listed