Esophageal Cancer Stage, Head and Neck Cancer
Conditions
Keywords
Head and Neck Cancer, Esophageal Cancer, endoscopic submucosal dissection, quality of life, median survival time
Brief summary
To summarise the outcomes of a treatment decision of patients with superficial esophageal carcinoma synchronously associated with head and neck cancer, that is endoscopic treatment for the superficial esophageal carcinoma plus surgery of the head and neck carcinoma.
Detailed description
As a same risk factor, such as heavy drinking and smoking, patients with head and ncek carcinoma are always suffering from synchronous esophageal squamous cell carcinoma. Previous studies illustrated that many patients with multiple esophageal lesions of early stage. In clinical practice, those patients are treated by extensive surgical resection of total pharyngo-laryngo-esophagectomy plus free jejunum interposition or gastric tube, then followed by chemoradiotherapy as standard treatment, resulting in a low quality of life for the patients, and due to the above mentioned disadvantages, many patients with synchronous superficial esophageal squamous cell carcinoma and head and neck carcinoma refused the surgery treatment. Our aims is to summarize the the outcomes of endoscopic treatment for the superficial esophageal carcinoma plus surgery of head and neck carcinoma.
Interventions
None listed
Sponsors
Yanqing Li
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
1. Patients with head and ncek carcinoma associated with synchronous superficial esophageal squamous cell carcinoma. 2. Patients agree to be treated with esophageal endoscopic submucosal dissection firstly, then accept surgery of head and neck carcinoma.
Exclusion criteria
1. Patients refuse a endoscopic submucosal dissection or surgery. 2. Patients with sever systemic disease, such as sever cardiopulmonary disease, renal failure and impaired blood coagulation. 3. Obstruction of the pharynx leading to a failure of insertion of endoscopy. 4. Patients with an advanced esophageal carcinoma evaluated by endoscopy.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The first day of food intake of enrolled patients | An average of 1week | The first day of food intake after surgery of the head and neck carcinoma |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| The relapse rate of the enrolled patients | an average of 2 years | the relapse rate of esophageal cancer or head and neck carcinoma respectively of the enrolled patients. |
| The hospital stay of enrolled patients | An average of 1 month. | The total hospital stay during the first hospitalization of the enrolled patients |
| The incidence of stenosis | an average of 2 years | The average interval of the stenosis |
| The severity of stenosis | an average of 2 years | The average diameter of the stenosis |
Countries
China
Contacts
Primary ContactYanqing Li
Outcome results
None listed