Retinopathy of Prematurity
Conditions
Brief summary
Because of the neonatologists reported that some infants had suffered from vomiting, bradycardia, hypotonia, and aspiration risk about 30-60 minutes after the fundus examination in the intensive care unit. The investigators observed the pupil dilation effects and side effects of tipple instillation of phenylephrine 2.5% plus tropicamide 0.5% ophthalmic drop combination which the investigators routinely used in ROP examination.
Detailed description
Purpose: To determine effect and vital change after topical application of phenylephrine 2.5% and tropicamide 0.5% three times for retinopathy of prematurity (ROP) examination in preterm infants. Methods: Pupillary diameter, blood pressure, pulse rate, and oxygen saturation were monitored before, and after up to 24 hours 60 ROP screening examinations.
Interventions
DRUGDrug used in the examination of premature infants.
to investigate side effects of eye drops used
Sponsors
Bulent Ecevit University
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
32 Weeks to 34 Weeks
Healthy volunteers
No
Inclusion criteria
* Infants who were first ROP examinations * infants born before 32 weeks.
Exclusion criteria
* Developmental ocular and/or systemic anomalies. * Drug use that can affect vital values * Unstable general condition * Food intolerance * Recurrent vomiting.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The mean pupillary diameter | an average of 1 year | will be measured with a ruler after 60 minutes instillation of mydriatic |
Outcome results
None listed