Effect of Composition and Timing of Ingestion of Fluids on the Urinary Excretion of Lithogenic Substances

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03447847

Enrollment

Registered

2018-02-27

Start date

2018-05-01

Completion date

2018-09-01

Last updated

2018-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Brief summary

Interventional crossover study on healthy volunteers aimed at evaluating the effect of the composition and timing of ingestion of different types of water on the urinary excretion of lithogenic substances; the study will also analyze the effect of potassium citrate on urine pH and lithogenic substances

Interventions

OTHERWater

1 liter of water in meals; 1 liter out of meals

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

OTHER

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 50 Years

Healthy volunteers

Yes

Inclusion criteria

* Age \>18 years

Exclusion criteria

* Chronic malabsorption * Recurrent urinary tract infections * History of kidney stones

Design outcomes

Primary

Measure	Time frame
Urine composition	Assessed the same day of water ingestion

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 18, 2026