Healthy Volunteers
Conditions
Brief summary
Bioavailability of dietary supplement formulations in healthy volunteers after a single oral dose.
Detailed description
Comparison of the bioavailability of 3 formulations with astaxanthin in healthy volunteers after single dose
Interventions
DIETARY_SUPPLEMENTAstaxanthin
an oral dose form
Sponsors
Algatechnologies Ltd.
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
21 Years to 50 Years
Healthy volunteers
Yes
Inclusion criteria
* Subjects who have signed an informed consent form and who meet all of the following entrance criteria may be enrolled in this clinical trial: Generally, healthy men and women who are 21 to 50 years of age, inclusive, at the baseline visit.
Exclusion criteria
* 1\. Are unwilling to follow the procedures of the trial, such as making visits or having their blood drawn. 2\. Have unintentionally lost or gained 10 or more kg of body weight in the last 3 months; 3. Have an acute illness (such as a severe cold or flu) or have been hospitalized within the past month for certain conditions; 4. Have severe co-morbid disease including cardiac, pulmonary, renal, hepatic, carotid, peripheral vascular disease, stroke, neurological, clotting disorders or active cancer; 5. Taking chronic drugs which interfere with lipids metabolism (statins or similar) 6. Consume alcohol at an elevated level (Defined as consumption of more than 10 standard alcoholic drinks per week. A standard alcoholic drink is defined as one bottle/can of beer or one glass of wine equals one portion of hard liquor). 7\. Consume carotenoids as food supplements. 8. Have a Body Mass Index (BMI) of less than 17 or greater than 35 m/kg2; 9. Have participated in a clinical trial in the past 4 weeks; 10. Have any disease or condition that in the investigator's opinion compromises the integrity of the clinical trial or the safety of the subject; 11. Smokers 12. Pregnant woman
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| plasma level | 0-48 hr | astaxanthin in plasma |
Countries
Israel
Outcome results
None listed