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Fournier's Gangrene and the Origin of the Infection as a Prognostic of Morbidity and Mortality, an Analysis of 121 Patients

Fournier's Gangrene and the Origin of the Infection as a Prognostic of Morbidity and Mortality, an Analysis of 121 Patients

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03443544
Enrollment
121
Registered
2018-02-23
Start date
2017-11-01
Completion date
2018-02-01
Last updated
2018-02-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fournier Gangrene, Fournier's Gangrene of Penis, Fournier's Gangrene of Scrotum

Keywords

fournier's, gangrene

Brief summary

Background: Fournier's gangrene it's a necrotizing infection of the genital area, with high morbidity and mortality. The site of infection its the origin of the necrotizing fasciitis. There are 4 well known origins of Fournier's gangrene: Testicular, Intestinal, Urinary and cutaneous, and its prognostic value has not been established yet, that's because the lack of case series with adequate number of patients. This is a retrospective study in which we evaluate the prognostic factors of every patient and its mortality compared with its origin area and multiple scores with their survival rates and hospital stay.

Detailed description

Objective: To evaluate origins of Fournier's gangrene as a prognostic value in the morbidity and mortality. Patients and methods: This is a retrospective study where patients from a single hospital from 2007 to 2016 were included. They were categorized in 4 groups matching the origin of infection. In every group categorizing with the origin of infection and determined severity factors, days of hospital stay, Fournier's gangrene severity index and mortality. A statistic analysis will be done using lineal multivariable analysis.

Interventions

PROCEDUREAggressive debridement

Aggressive debridement of the tissues undergoing fascitis

Sponsors

Hospital Universitario Dr. Jose E. Gonzalez
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
MALE
Healthy volunteers
No

Inclusion criteria

* Male Patient * Fournier's Gangrene * All patients treated with two antibiotics * All patients undergone with aggressive debridement

Exclusion criteria

* Female * Not having Fournier's Gangrene

Design outcomes

Primary

MeasureTime frameDescription
Fournier's Gangrene Severity Index0-24 hoursA score to predict mortality in this kind of patients
Hospital stay ( in days)0 to 2 monthsThe patients hospital stay
Couture24 hoursPositive or negative couture and the bacterias growing in the abscess

Secondary

MeasureTime frameDescription
Diabetes mellitus0 - 100 yearsif the patient had diabetes mellitus type 2 or not
Tobacco smoking0 - 100 yearsif the patient smokes or not
Hypertension0 - 100 yearsif the patient had arterial hypertension or not
Alcohol drinking0 - 100 yearsif the patient drinks alcohol or not

Countries

Mexico

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026