Long-term Assessment of Organ Functions Among Survivors of Severe Acute Respiratory Syndrome

The 15-year Impact of Severe Acute Respiratory Syndrome on Organ Functions, Exercise Capacity, and Quality of Life in Survivors.

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03443102

Enrollment

150

Registered

2018-02-22

Start date

2018-01-25

Completion date

2018-12-01

Last updated

2018-02-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Long-Term Survivors, SARS Virus

Brief summary

SARS-CoV has caused severe epidemic respiratory disease in human populations. By July 2003, a total of 8,096 probable cases of SARS had been reported including 774 deaths in 27 countries, around one-third of which were health care workers (HCWs). Previous studies have been reported about long-term impacts of SARS infection, including lung function deficiency, steroid-induced osteonecrosis, reduced exercise capacity, and impairment in health-related quality of life (HRQoL). HCWs, especially nurses, have been reported to experience greater psychological distress, particularly increased levels of posttraumatic stress symptomatology (PTSS). But the very complex impacts of this fatal infection on HCWs have not been fully elucidated. It is thus important to follow these occupational patients to detect and manage multi-organ sequelae and functional impairment.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Yes

Inclusion criteria

* Health care workers who were working at Peking University People's Hospital during the SARS epidemic in 2002-2003

Exclusion criteria

* Refusal to continue the study

Design outcomes

Primary

Measure	Time frame	Description
All-cause disability	Evaluations would be finished within 90 days after enrollment.	Disabilities arising from physical injuries and/or mental stresses

Secondary

Measure	Time frame	Description
Cardiopulmonary function	Evaluations would be finished within 90 days after enrollment.	The interrelationship between the workings of the heart and lung organs would be assessed by assessed by 6MWT (6-min walk test)
Life Life quaities mental distress	Evaluations would be finished within 90 days after enrollment.	Quality of life would be assessed by the Medical Outcomes Study 36-item short form version 2 (SF-36)

Countries

China

Contacts

Primary ContactYali Zheng, Dr

yali_zheng@126.com+8615011451515

Backup ContactJia Li, Dr

lj10120@sina.com+8613661310120

Outcome results