Evaluation of Periodontal Diseases and Obesity in Women

The Effects of Obesity and Periodontitis on Biochemical Parameters in Women Subjects

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03442920

Enrollment

Registered

2018-02-22

Start date

2014-12-29

Completion date

2016-01-10

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity, Periodontal Diseases

Keywords

obesity, periodontal diseases, gingival crevicular fluid, saliva, serum

Brief summary

The aim of this study was to evaluate the effect of obesity and exercise on periodontal and biochemical parameters \[serum, saliva and gingival crevicular fluid (GCF) adipokines (interleukin-1β, tumor necrosis factor-α, leptin, resistin and adiponectin)\].

Detailed description

It is thought that adipokines may play a role on periodontal disease in obese subjects, periodontal disease may also aggravate the existing systemic disease by changing the inflammatory parameters in the body. The aim of this study was to evaluate the effect of obesity and exercise on periodontal and biochemical parameters \[serum, saliva and gingival crevicular fluid (GCF) adipokines (interleukin-1β, tumor necrosis factor-α, leptin, resistin and adiponectin)\].

Interventions

OTHERExercise

This group made exercise for 12 week/3 times a week.

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Primary purpose

DIAGNOSTIC

Masking

NONE

Eligibility

Sex/Gender

FEMALE

Healthy volunteers

Yes

Inclusion criteria

* Being women, * Older than 18 yrs old, * Not being pregnant, * Not being disabled, * For study group; being obese, not for healthy group being systemically health and in normal weight * Not treated periodontological in the last 6 months

Exclusion criteria

* Younger than 18 yrs old, * Smokers who smokes more than 10 cigarettes in a day, * Uncontrolled systemic diseases, * Having periodontal treatment * who needs antibiotic prophylaxis

Design outcomes

Primary

Measure	Time frame	Description
Biochemical variables GCF	12 week	TNF-A, IL-1B,concentrations levels (pg/µl)

Secondary

Measure	Time frame	Description
Biochemical variables_Saliva	12 week	TNF-A, IL-1B,concentrations levels (pg/µl)
Biochemical variables_Serum	12 week	TNF-A, IL-1B,concentrations levels (pg/µl)

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026