Swallowing and Voice Outcomes After Thyroidectomy

Objective Analysis of Swallowing and Functional Voice Outcomes After Thyroidectomy: A Prospective Cohort Study

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03436186

Enrollment

Registered

2018-02-19

Start date

2013-01-01

Completion date

2015-06-30

Last updated

2018-02-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Functional Voice and Swallowing Outcomes

Keywords

Thyroidectomy, voice, swallowing problems, dysphagia

Brief summary

Impairment in voice and swallowing functions are common after thyroidectomy. The investigators aimed to evaluate the objective functional voice and swallowing outcomes in a series of patients undergoing thyroidectomy. according to the study, even in the absence of recurrent laryngeal nerve injury, subjective and objective swallowing and voice alterations do occur after thyroidectomy.

Detailed description

A total of 43 consenting patients who underwent thyroidectomy were prospectively recruited. Subjective evaluation of swallowing was assessed with 'Swallowing Impairment Score' and 'MD Anderson Dysphagia Inventory'. Fiberoptic endoscopic evaluation of swallowing (FEES) was applied for objective evaluation. Also, functional oral intake scale (FOIS) and functional outcome swallowing scale (FOSS) were used for swallowing assessment. Voice evaluation was assessed with videostrobolaryngoscopy (VSL) and 'The Multi-Dimensional Voice Program (MDVP)' was used for capturing and analyzing the voice samples. All evaluations were performed preoperatively and on 1st day, 2nd week and 6th months postoperatively.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

27 Years to 78 Years

Healthy volunteers

Yes

Inclusion criteria

* patients undergoing thyroidectomy

Exclusion criteria

* Patients who were diagnosed with thyroid carcinoma preoperatively * Having history of previous neck surgery, * History of radiotherapy at head and neck region, * Vocal cord paralysis, * neuromuscular dysfunction, * larynx, esophagus and chest pathology * who did not want to be involved in the study

Design outcomes

Primary

Measure	Time frame	Description
functional oral intake score	6 months	comparison of functional oral intake score of specific functional limitation between groups
the intake of fluid and thickened liquid food	6 months	comparison of the intake of fluid and thickened liquid food between pre- and post-operative scores
light and moderate residual accumulation in solid food intake	6 months	comparison of light and moderate residual accumulation in solid food intake between groups
MD Anderson dysphagia inventory (MDADI)	6 months	comparison of MD Anderson dysphagia inventory (MDADI) between pre- and post-operative groups
voice evaluation	6 months	comparison of standard deviation of average, fundamental frequency and degree of subharmonics between groups
Swallowing impairment score (SIS)	6 months	comparison of Swallowing impairment score (SIS) between pre- and post-operative groups

Secondary

Measure	Time frame	Description
objective and subjective values correlation	6 months	Subjective data showed no correlation with objective findings (p\>0.05)

Outcome results