Healthy
Conditions
Brief summary
Healthy reclining adult volunteers, with Valsalva manoeuver, Muller manoeuver, light continuous positive airway pressure by mask, passive leg raising, and maximal hand-grip. Ultrasound heart images captured before and during.
Detailed description
With focus on atrial wall strain and strain-rate, In healthy volunteer adult subjects, heart ultrasound is recorded during resting, Valsalva manoeuver, Muller manoeuver, passive leg raising, and handgrip. Echocardiographic recordings are made before and during each intervention. Participants are otherwise resting in a reclined position.
Interventions
OTHERSimple breathing manuevers during brief echocardiographic imaging
Valsalva, Muller, light mask CPAP, leg raising, hand grip.
Sponsors
Region Västerbotten
Umeå University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Intervention model description
Healthy reclining adult volunteers, with Valsalva manoeuver, Muller manoeuver, light continuous positive airway pressure by mask, passive leg raising, and maximal hand-grip. Ultrasound heart images captured before and during.
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
Yes
Inclusion criteria
* healthy adults
Exclusion criteria
* known heart or lung disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in atrial wall stress during breathing manoeuver, compared to control measurement immediately before the breathing manoeuver | 30 seconds, i.e. control measurement and then measurement during breathing manoeuver observed from same breathing/measurement sequence | Echocardiographic measure, comparing control measurement to measurement during breathing manoeuver |
Countries
Sweden
Outcome results
None listed