Chronic Kidney Diseases, Hemolysis
Conditions
Brief summary
To evaluate the effect of hemodialysis on various ophthalmologic parameters in patients with end-stage kidney disease (ESRD).
Detailed description
Subjects: patients with ESRD undergoing hemodialysis at the Dialysis Center of Hanyang Guri Hospital Ocular parameters: visual acuity, intraocular pressure, axial length, OCT Other systemic parameters: body weight, ultrafiltration volume, and systolic/diastolic blood pressure All measurements were performed near the dialysis center. Measurements were performed on Monday (for patients who underwent dialysis sessions on Monday, Wednesday, and Friday) or Tuesday (for patients who underwent dialysis sessions on Tuesday, Thursday, and Saturday. All parameters were measured before and after the hemodialysis.
Interventions
OTHERophthalmologic exams
ophthalmologic exams such as vision, intraocular pressure, axial length and optical coherence tomography
Sponsors
Hanyang University
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
20 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* 1\) patients who are regularly dialyzed in our dialysis room to participate in the study * 2\) patients who agree with our study protocol * 3\) patients who have unstable general condition
Exclusion criteria
* 1\) previous intraocular surgery, (2) baseline IOP greater than 22 mmHg, (3) presence of glaucomatous optic disc changes including excavation, thinning, or notching of the neuroretinal rim, (4) axial length greater than 26 mm, and (5) combined macular and retinal diseases such as central serous chorioretinopathy and age-related macular degeneration, except diabetic retinopathy.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| changes of retinal and choroidal thickness after hemodialysis | immediately (within 10 minutes) before and after hemodialysis | retinal & choroidal thickness on OCT |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| changes of foveal vascular density using optical coherence tomography-angiography (OCTA) after hemodialysis | immediately (within 10 minutes) before and after hemodialysis | vessel density on OCTA |
| the effect of hemodialysis (HD) on anterior chamber angle by anterior segment optical coherence | immediately (within 10 minutes) before and after hemodialysis | intraocular pressure, retinal thickness, anterior chamber angle |
Outcome results
None listed