Periodontitis, Adult
Conditions
Brief summary
The study will be conducted at the Department of Periodontology, Cliniques universitaires Saint Luc. Patients diagnosed with Generalized Chronic Periodontitis (GChP) based on the current classification of the American Academy of Periodontology will be included. Detailed medical, periodontal and dental history will be obtained. Those who will fulfill the inclusion/exclusion criteria will be invited to participate in the study.
Detailed description
The study will be conducted at the Department of Periodontology, Cliniques universitaires Saint Luc. The patients will be informed in detail of the nature and course of study, and will sign informed consent prior to engagement in the study. Patients diagnosed with GChP based on the current classification of the American Academy of Periodontology will be included. Detailed medical, periodontal and dental history will be obtained. Those who will fulfill the inclusion/exclusion criteria will be invited to participate in the study.
Interventions
The side of the mouth receiving the subgingival irrigations of povidone iodine 10% (test group)
DRUGSaline Solution
The other side of the mouth will be irrigated with a sterile saline solution (control group)
Sponsors
Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Intervention model description
20 patients (=40 half-mouth); 20 half-mouth per group
Eligibility
Sex/Gender
ALL
Age
30 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* ≥ 30 years of age * At least 15 teeth (excluding third molars and teeth with advanced decay indicated for extraction) * Any history of periodontal treatment in the previous 6 months * No removable prosthesis * A minimum of 6 teeth with at least one site each with periodontal probing depth (PPD) and clinical attachment level (CAL) ≥5 mm * At least 30% of the sites with PPD and CAL ≥4 mm and bleeding on probing (BOP)
Exclusion criteria
* Any sensitivity or allergy to any of the products that will be used in the study * Thyroid dysfunction * Systemic disease (ASA II or more) * Need for antibiotic pre-medication for routine dental therapy * Antibiotic therapy in the previous 3 months * Pregnancy and breastfeeding * Current smokers (more than 5 cigarettes a day)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Percentage of subjects reaching ≤ 4 mm in periodontal sites with PPD ≥ 5 mm | up to 6 months | The primary objective of this study is to determine the effect of PVI on periodontal probing depth (PPD). |
Countries
Belgium
Contacts
Primary ContactSelena Toma, Parodontologist
Backup ContactSelma Kessler, Dentist
Outcome results
None listed