Sleep
Conditions
Keywords
Premature infant, sleep state, body movement, neurodevelopmental outcome
Brief summary
Sleep is a key factor for normal brain development of the newborn. However, it is poorly studied and little is known about its characterization, especially in premature infants. Body movements during sleep are easy to evaluate but studies on their relationship to normal sleep states are scarce and limited. This project aims to characterize body movements during sleep, assessed by electroencephalography, in very premature infants. Then, a correlation between body movements, sleep organization and neurodevelopmental outcome will be evaluated at 3 years of age.
Interventions
DIAGNOSTIC_TESTelectroencephalography
Sleep states definition by electroencephalograpy
Sponsors
Central Hospital, Nancy, France
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
10 Days to 15 Days
Healthy volunteers
No
Inclusion criteria
* Infants born between 26 and 32 weeks gestation
Exclusion criteria
* Genetic abnormality * Neurological pathology such as intraventricular hemorrhage \> grade 2 * Any medication know for altering electroencephalography recording
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Body movements evaluation during sleep | 3 months | number of movements observed according to sleep states |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Sleep states organization | 3 months | sleep states characterization by electroencephalography according to postmenstrual age |
| Type of movements observed during sleep | 3 months | Movements characterization according to sleep states |
| Neurodevelopmental outcome | 3 years | neuropsychomotor evaluation by Bayley psychometric test |
Countries
France
Outcome results
None listed