Cross-sectional Study of Prevalence Rate of Abdominal Aortic Aneurysm in OSAHS Patients From BTCH

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03431038

Enrollment

1800

Registered

2018-02-13

Start date

2017-09-01

Completion date

2020-06-01

Last updated

2018-02-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

AAA - Abdominal Aortic Aneurysm, Sleep Apnea, Obstructive

Brief summary

This study explore AAA prevalence in OSAHS patients by ultrasound screening and try to analysis risk factors of AAA in OSAHS patients.

Detailed description

Abdominal aortic aneurysm (AAA) is an extremely high mortality disease, and ultrasound has been recommended for the screening of AAA, which is highly sensitive and specific. Studies have shown that screening for AAA in the population can significantly reduce deaths from ruptured abdominal aortic aneurysms. However, those study mainly focus on cardiovascular disease patients or general population, no previous study target on obstructive sleep apnea hypopnea syndrome (OSAHS) population. Retrospective studies show that the incidence of apnea syndrome in patients with abdominal aortic aneurysm is higher than that in the control group, which suggests that OSAHS may be one of the causes of abdominal aortic aneurysm. At present, there is no relevant research on the screening of AAA in OSAHS population. The main objective of this study was to screen the prevalence of AAA in OSAHS population by a cross-sectional study.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

45 Years to No maximum

Healthy volunteers

Inclusion criteria

* All patients who accept respiratory sleep monitoring in the department of ENT, BTCH, aged over 45 years, from 2018-01-01 to 2019-12-30

Exclusion criteria

* 1\. Any previous diagnosis of AAA history; * 2\. Received AAA related treatment; * 3\. Past imaging test result suggested increased diameter of the abdominal aorta. * 4\. Poor compliance; refused to follow the requirements set in this study follow-up, and refused to sign informed consent.

Design outcomes

Primary

Measure	Time frame	Description
Diameter of aorta	0-48 hours	Diameter of aorta measured by ultrasound

Secondary

Measure	Time frame	Description
ABI	0-48 hours	Ankel brachal index measured by Angiolab 2 - Phlebolab Doppler-System
Carotid artery stenosis	0-48 hours	Carotid artery stenosis measured by ultrasound

Countries

China

Outcome results