A Study to Evaluate Effectiveness and Safety of Surgeries in Elderly NSCLC Patients

A Multi-centre Real-world Non-interventional Observational Study to Evaluate Effectiveness and Safety of Surgeries in the Chinese Early-stage Patients With Non-small Cell Lung Cancer

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03429673

Enrollment

10885

Registered

2018-02-12

Start date

2017-12-01

Completion date

2018-03-30

Last updated

2018-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-small Cell Lung Cancer

Keywords

Chinese, real-world evidences, NSCLC, surgeries

Brief summary

The trial was designed to compare effectiveness and safety of surgeries in the patients with non-small cell lung cancer

Detailed description

The trial is a multi-centre, real-world, non-interventional, observational study. The Chinese elderly pathologically diagnosed patients with early-stage non-small cell lung cancer enrolled from 2015 to 2017 who received lobectomy or segment/wedge dissection were included and the study data on patient demographic/tumor biological characteristics, and clinical treatments were retrospectively collected to evaluate effectiveness and safety of the surgeries.

Interventions

PROCEDURESurgeries

Lobectomy or segment/wedge dissection

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

65 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients who received surgeries from 2014 to 2017; * Patients who received lobectomy or segment/wedge dissection; * Pathologically diagnosed patients with non-small cell lung cancer; * Patients with age \>=65 years old.

Exclusion criteria

* Patients who received neoadjuvant therapy prior to surgery.

Design outcomes

Primary

Measure	Time frame	Description
Overall survival	2015-2017	Overall survival

Other

Measure	Time frame	Description
Overall survivals in the subgroups	2015-2017	Overall survivals in the subgroups categorised by age, tumor size, and clinical/pathological staging
Impact factors of overall survival	2015-2017	Impact factors of overall survival as measured by patient demographic/tumor biological characteristics
Death rate within 30/90 days after surgeries	2015-2017	Death rate within 30/90 days after surgeries
Incidence of perioperative complications	2015-2017	Incidence of perioperative complications

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 21, 2026