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Psychological Status and Related Factors of Thyroid Related Eye Disease

Psychological Status and Related Factors of Thyroid Related Eye Disease

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03426696
Enrollment
300
Registered
2018-02-08
Start date
2017-12-01
Completion date
2018-12-31
Last updated
2020-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thyroid Related Eye Disease

Keywords

psychological status, Related Factors, Thyroid Related Eye Disease

Brief summary

The purpose of this study is to evaluate the psychological status of Thyroid Related Eye Disease.

Detailed description

The purpose of this study is to evaluate the psychological status of patients of Thyroid Related Eye Disease over 16 years old, and to analyze the related factors of them.

Interventions

BEHAVIORALpsychological condition

Graves ́ ophthalmopathy quality of life questionnaire, Symptom checklist 90(SLC-90), Hamilton anxiety scale(HAMA), Somatic self-rating scale(SSS), MATRICS Consensus Cognitive Battery (MCCB), Hamilton depression scale(HAMD)

Sponsors

Huijing Ye
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
16 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* over 16 years old * diagnosed as Thyroid Related Eye Disease

Exclusion criteria

* any uncontrolled clinical problems

Design outcomes

Primary

MeasureTime frameDescription
Quality of life questionnaire of patients of Thyroid Related Eye DiseaseimmediatelyGraves ́ ophthalmopathy quality of life questionnaire (GO-QoL) , The GO-QoL contains 8 questions on visual functioning and 8 questions on appearance; answers on each subscale are transformed to scores ranging from 0 (worst) to 100 (best).

Secondary

MeasureTime frameDescription
Symptom checklist 90(SLC-90)immediatelyIt consists of 90 items yielding nine scores along primary symptom dimensions and three scores among global distress indices. The primary symptom dimensions that are assessed are somatization, obsessive-compulsive, interpersonal sensitivity, depression, anxiety, hostility, phobic anxiety, paranoid ideation, psychoticism, and a category of additional items which helps clinicians assess other aspect of the clients symptoms. Positive standard includes: total score 160 points or more, or positive items \> 43 points, or any item \> 2 points.
Hamilton anxiety scale(HAMA)immediatelyThis scale includes 14 items. All projects rated as: asymptomatic, light, medium, heavy, or very heavy. If the total score more than 29 points, there could be severe anxiety; more than 21 points, affirmation have obvious anxiety; more than 14 points, there must be some anxious; more than 7 points might be anxious; if less than 6 points, patients without anxiety symptoms.
Somatic self-rating scale(SSS)immediatelySomatic self-rating scale can let the doctor fully understand patients' mood and somatization symptoms. If the selected items scores more than 30 points, the patient may need to clinic treatment.
Hamilton depression scale(HAMD)immediatelyIt is the most common depression clinical application scale. Lower score presents lighter condition, and if the illness is heavier, the higher is the score. There is no depression symptoms for score less than eight points.
Young manic rating scale(YMRS)immediatelyThe Young Mania Rating Scale (YMRS) is a diagnostic questionnaire commonly used to evaluate manic symptoms in patients with bipolar 1 disorder and to assess treatment efficacy in clinical trials. This rating scale comprises eleven items (elevated mood, increased motor activity - energy, sexual interest, sleep, irritability, speech - rate and amount, language-thought disorder, content, disruptive-aggressive behavior, appearance, and insight). The total YMRS score is calculated as the summation of each of the eleven individual item scores.Lower score presents lighter condition, and if the illness is heavier, the higher is the score.There is no manic symptoms for score less than five points.

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026