Gingival Recession, Localized, Low-Level Light Therapy, Transplants, Wounds and Injuries
Conditions
Keywords
Free gingival graft, Low level laser therapy, Shrinkage
Brief summary
The present placebo-controlled parallel design clinical study was planned to determine the effect of low level laser therapy on clinical periodontal conditions and dimensions of free gingival graft as well as postoperative pain levels in the surgical area.
Detailed description
Background: Shrinkage of the free gingival graft (FGG) and patient's discomfort during healing period are important concerns. Therefore, this study aimed to evaluate the effect of low level laser therapy (LLLT) in terms of enhancing wound healing, reducing graft shrinkage and postoperative pain. Methods: Thirty patients were randomly assigned to receive either FGG+ LLLT (test, n = 15) or FGG + placebo LLLT (control, n = 15). In the test group, a diode laser (aluminum-gallium-arsenide, 810 nm, 0.1 W, continuous mode, time of irradiation:60 s, energy density: 6 J/cm2, spot size:0.5 cm) was applied immediately after the FGG surgery and 1,3,7, and 14 days later. The control group received the same sequence of irradiation with the laser-off. Comparison of the graft surface areas between groups at 1st, 3rd and 6th months were made with an image-analyzing software. Complete wound epithelization, visual analogue scale (VAS) pain score of recipient site and the number of analgesic used were evaluated after the surgery.
Interventions
DEVICECheseeTM Diode Laser
low level laser therapy was utilized adjunct with free gingival graft.
OTHERClinical examination
The shrinkage of the graft area was calculated according to the differences between the graft area at baseline, 1st, 3rd, and 6th months. Epithelization was determined via bubbling test by using 3% hydrogen peroxide (H2O2) at 7, 14, 21, and 28 days after surgery.
Sponsors
Abant Izzet Baysal University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Intervention model description
Randomized placebo-controlled parallel design
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* Patients \>18 years old * Patients presenting Class I or II Miller gingival recession on vital incisors in the mandibular anterior region with no caries or restoration * The included teeth had also keratinized gingiva \<2 mm; PI and GI\<1. * The patients had to be systemically healthy and non-smokers.
Exclusion criteria
* Patients presenting active periodontal disease and probing depth \>3 mm; taking medications that would interfere with the wound-healing process or that contraindicate the surgical procedure; * Pregnant or lactating women; * Patients who underwent periodontal surgery in the study area; * Patients with orthodontic therapy in progress were excluded.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Graft shrinkage | 1-, 3-, and 6-months after FGG surgery | The shrinkage of the graft area was calculated according to the differences between the graft area at baseline, 1st, 3rd, and 6th months. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Epithelization | 7, 14, 21, and 28 days after FGG surgery | Epithelization was determined via bubbling test by using 3% hydrogen peroxide (H2O2). This test was carried out at 7, 14, 21, and 28 days after surgery. |
Outcome results
None listed