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Hepatitis B Virus Prevalence and Risk Factors in Belgium

Hepatitis B Virus Prevalence and Risk Factors in Middle Limburg Belgium: the Importance of Migration.

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03425513
Acronym
HBVBE
Enrollment
1131
Registered
2018-02-07
Start date
2017-05-12
Completion date
2017-11-27
Last updated
2020-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hepatitis B

Keywords

Belgium, Prevalence, Risk factor, Ethnicity, Linkage of care

Brief summary

The aim of this study was to evaluate the current prevalence and risk factors of hepatitis B virus (HBV) infection in a multi-ethnic neighbourhood situated in Middle Limburg, Belgium. Additionally, the investigators will determine linkage of care in hepatitis B surface antigen (HBsAg) positive subjects.

Detailed description

Although the HBV prevalence is generally low in Western countries, such as Belgium, pockets of higher HBV prevalence exist in areas with large immigrant populations. Therefore national prevalence figures can underestimate the burden of HBV infection. The prevalence of chronic HBV in the population-based study in 2003 is believed to be an underestimate due to under-representation of the non-Belgian population. Moreover, by this time there are no data regarding the risk factors for HBV infection in the general population of Belgium. Even in low-prevalence areas such as Belgium, HBV prevention and control is a public health priority, particularly since safe and effective vaccines are available. The aim of this study was to evaluate the current prevalence and risk factors of HBV infection in a multi-ethnic neighbourhood situated in Middle Limburg, Belgium. Additionally, the investigators will determine linkage of care in hepatitis B surface antigen (HBsAg) positive subjects.

Interventions

DIAGNOSTIC_TESTHepatitis B serology

A serum specimen will be taken and assessed for hepatitis B serology (HBsAg and anti-HBc antibodies).

OTHERQuestionnaire

Participants will be asked to fill in a questionnaire regarding demographic characteristics, known viral hepatitis status and risk factors for HBV infection.

Sponsors

Hasselt University
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
Yes

Inclusion criteria

* Age between 18 and 70 * Males and females

Exclusion criteria

/

Design outcomes

Primary

MeasureTime frameDescription
Seroprevalence of current HBV infection in the Middle Limburg population1 daySerum HBsAg
Seroprevalence of past or current HBV infection in the Middle Limburg population1 daySerum anti-HBc antibodies

Secondary

MeasureTime frameDescription
Assess risk factors for current HBV infection in the Middle Limburg population1 dayCombine results from (1) serum HBsAg with (2) questionnaire regarding demographic characteristics, known viral hepatitis status and risk factors for HBV infection.
Assess risk factors for past or current HBV infection in the Middle Limburg population1 dayCombine results from (1) serum anti-HBc antibodies with (2) questionnaire regarding demographic characteristics, known viral hepatitis status and risk factors for HBV infection.

Countries

Belgium

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026