General Anesthesia
Conditions
Brief summary
The aim of this comparative analysis is to evaluate the reliability of PLE value as an anesthetic depth indicator
Detailed description
1. To evaluate the reliability of PLE value as an anesthetic depth indicator, the investigators compare PLE value with BIS score during induction and emergence of general anesthesia using propofol target controlled infusion. 2. In addition, the investigators verify whether or not the facial nerve integrity monitoring affects the efficacy for PLE and BIS values as an anesthetic depth indicator.
Interventions
DEVICEPLE and BIS
Investigators attach the PLE and BIS sensors on the forehead of the patients undergoing facial nerve integrity monitoring during general anesthesia using total intravenous anesthetics
Sponsors
Hallym University Medical Center
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
20 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Patients who scheduled for otopharyngeal surgery under facial nerve integrity monitoring requiring general anesthesia and American Society of Anesthesiology (ASA) physical status 1 or 2
Exclusion criteria
* Patient who has been taken anticonvulsant agents, sedatives, and hypnotics * Patient who has central nerve system disease, neurological disorder * Patient with hypersensitivity to anesthetics
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| PLE value during induction and emergence of general anesthesia | Through study completion, an average of fifteen months | Investigators measure the PLE value as an anesthetic depth indicator before the injection of propofol, at the time point of no response to verbal command, before and after intubation, and at the time point of response to verbal command during emergence of anesthesia. The PLE value will be reported in a score ranging from 0 (burst suppression or deep sedated) to 100 (full awake). |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| BIS value during induction and emergence of general anesthesia | Through study completion, an average of fifteen months | Investigators measure the BIS value as an anesthetic depth indicator before the injection of propofol, at the time point of no response to verbal command, before and after intubation, and at the time point of response to verbal command during emergence of anesthesia. The BIS value will be reported in a score ranging from 0 (burst suppression or deep sedated) to 100 (full awake). |
| PLE value during facial nerve integrity monitoring | Through study completion, an average of fifteen months | Investigators measure the PLE value at the time points of facial nerve integrity monitoring. The PLE value will be reported in a score ranging from 0 (burst suppression or deep sedated) to 100 (full awake). |
| BIS value during facial nerve integrity monitoring | Through study completion, an average of fifteen months | Investigators measure the BIS value at the time points of facial nerve integrity monitoring. The BIS value will be reported in a score ranging from 0 (burst suppression or deep sedated) to 100 (full awake). |
Countries
South Korea
Contacts
Primary ContactKyung Mi Kim, Ph.D.
Outcome results
None listed