Cardiovascular Diseases, Death, Neoplasms
Conditions
Keywords
nutrition, physical activity, lifestyle, smoking
Brief summary
The European Prospective Investigation into Cancer and Nutrition in Norfolk is a population based prospective study of approximately 25,000 men and women resident in Norfolk United Kingdom. They were aged 39-79 years when first recruited from general practice age sex registers at baseline assessment 1993-1997. While part of a ten country half million participant European collaboration originally aimed to investigate diet and other lifestyle determinants of cancer, the objectives of the Norfolk cohort from inception were expanded to encompass the trajectory of health, ill health and mortality in a population over time and to examine the biological and lifestyle determinants of health and chronic disease.
Detailed description
The European Prospective Investigation into Cancer and Nutrition in Norfolk is a population based prospective study of approximately 25,000 men and women resident in Norfolk United Kingdom. They were aged 39-79 years when first recruited from general practice age sex registers at baseline assessment 1993-1997. While part of a ten country half million participant European collaboration originally aimed to investigate diet and other lifestyle determinants of cancer, the objectives of the Norfolk cohort from inception were expanded to encompass the trajectory of health, ill health and mortality in a population over time and to examine the biological and lifestyle determinants of health and chronic disease. Detailed data on sociodemographic, lifestyle, medical and family history were collected and a biological sample bank including urine and blood samples established. Participants have been followed up through repeat examinations, mailed questionnaires as well as through record linkage with routine health records including death certification by cause, cancer registration and hospital admissions by cause till present.
Interventions
BEHAVIORALdiet
lifestyle factors
Sponsors
Medical Research Council
Cancer Research UK
University of Cambridge
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
39 Years to 79 Years
Healthy volunteers
Yes
Inclusion criteria
* Willing to participate * On general practice age sex registers in Norfolk, United Kingdom in 1993-1997
Exclusion criteria
* Not willing to participate in study * terminal illness
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| neoplasms | Through 25 years | cancer incidence |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| cardiovascular diseases | through 25 years | incidence of cardiovascular diseases |
| death | through 25 years | total mortality by cause |
Other
| Measure | Time frame | Description |
|---|---|---|
| fractures | through 25 years | incident fractures |
| diabetes mellitus | through 25 years | incident diabetes |
Outcome results
None listed