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Vibration Induced Reflex Responses and Estimation of TVR

Vibration-induced Reflex Responses and Estimation of Tonic Vibration Latency

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03424551
Acronym
VIRR&TVR
Enrollment
40
Registered
2018-02-07
Start date
2018-01-23
Completion date
2018-03-23
Last updated
2019-08-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Muscle, Physiology

Keywords

vibration, muscle spindle, H reflex, tonic vibration reflex

Brief summary

The aim of this study is to estimate tonic vibration latency and whole body vibration reflex latency

Detailed description

This study was included 17 patients with spastic spinal cord lesions and 23 healthy control. Soleus T-reflex, soleus H-reflex, soleus tonic vibration reflex (TVR), and reflex muscle response induced by whole body vibration was evaluated this study. To obtain the H-reflex response, the tibial nerve in the popliteal region was stimulated by using a stimulator (FE155 Stimulator HC ADInstrument, Oxford UK) with 1 ms-pulse current. The records was taken with the Ag / AgCl electrodes (Kendall ®Coviden, self-adhesive electrodes) placed on skin according to the SENIAM protocol. To obtain T-reflex response, an electronic reflex hammer (Elcon 100-150 Germany) was used. After H-reflex and T reflex records at rest, to obtain Tonic vibration reflex, local vibration was applied to the Achilles tendon at 50, 85, 140, 185, 235 and 265 Hz. To obtain the reflex response induced by Whole body vibration, vibration was applied at 35, 37, 39, 41, 43 and 45 Hz. Tibial nerve stimulation was performed again to determine Hmax during whole body vibration and local vibration.H-reflex records was taken while the subject is sitting on a chair. The data was recorded with the PowerLab data acquisition device (ADInstrument Oxford UK). For Whole-body vibration, PowerPlate Pro5 (London UK) was used.

Interventions

DEVICEvibrator

Local or whole body vibration was applied at six different frequencies

Sponsors

Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Lead SponsorOTHER_GOV

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
20 Years to 45 Years
Healthy volunteers
Yes

Inclusion criteria

spinal cord injury patients: * Spastic spinal cord lesion * Patients between the ages of 20 and 45

Exclusion criteria

for spinal cord injury patients * Accompanying trauma 1. Lower extremity fracture 2. Lower extremity peripheral nerve lesions 3. Head trauma * Autonomic dysreflexia * Heterotopic ossification * Lesions in calf skin * Excessive spasticity (Ashwort4) / Contracture (knee, hip, footbath) * Peripheral nerve-vascular diseases / muscle diseases * Pressure ulcer (\> Grade 2) Inclusion criteria for Control * Ages 20 and 45 old years * Both sex * Healthy volunteers

Design outcomes

Primary

MeasureTime frameDescription
Presynaptic inhibition level1 dayChange in Hmax amplitude during vibration

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026