Study of Rotatory Vestibular Tests in Major Depression Patients and Healthy Control Subjects.

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03421847

Enrollment

Registered

2018-02-05

Start date

2005-07-01

Completion date

2006-12-15

Last updated

2018-02-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression, Vestibular Disorder

Keywords

depression, vestibular disorder, rotatory test, electronystagmography

Brief summary

This study evaluates the vestibular activity in major depression patients and healthy controls using the rotatory test and electronystagmography.

Detailed description

Previous studies showed abnormal vestibular activity in major depression patients using caloric vestibular tests. The present study investigates the vestibular response to vestibular rotatory tests in major depression subjects and healthy controls.

Interventions

DIAGNOSTIC_TESTRotatory vestibular test

We will measure Depression and Healthy subjects vestibular activity by Rotatory Vestibular tests

Study design

Observational model

CASE_CONTROL

Time perspective

OTHER

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* male and females adults (18 years or older) * met the Diagnosing and Statistical Manual of Mental Disorders (DSM-IV-R, American Psychiatric Association, 2000) criterion. * had a score of 12 or more in the Hamilton Rating Scale, 21 items for Depression. * with or without actual pharmacological treatment, except benzodiazepines that were suspended 24 hours before the rotary test when corresponding.

Exclusion criteria

* pregnant women * neurologic disorders.

Design outcomes

Primary

Measure	Time frame	Description
Vestibular Activity	Vestibular rotatory test for each participant is about 50- 60 minutes. One rotatory test per participant.	The primary outcome corresponds to the vestibular activity. The vestibular stimulation provided by the rotatory chair is sensed by the inner ear´s vestibular receptors and generates reflex ocular movements(Vestibulo Ocular Reflex) registrated by electronystagmography. The main outcome corresponds to the asymmetry of the vestibular activity between both ears.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 25, 2026