Nutrient Mixtures and Neurodevelopment

Prenatal and Childhood Nutrient Mixtures Predict Neurodevelopmental Outcomes Among Children in Mexico City

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03420872

Enrollment

329

Registered

2018-02-05

Start date

2006-09-15

Completion date

2018-08-15

Last updated

2019-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neurodevelopment

Keywords

Nutrition, Nutrients, Mixtures, Neurodevelopment, Prenatal, Children

Brief summary

Background: Adequate levels of beneficial nutrients are important for neurodevelopment. Although, nutrients are ingested in combination, considering nutrients as a mixture has not been studied with respect to health, such as neurodevelopment. Objective: To examine the impact of prenatal and childhood nutrition mixtures on neurodevelopment. Design: Participants included mother-child pairs in the Programming Research in Obesity, Growth Environment and Social Stress (PROGRESS) prospective birth cohort in Mexico City. Prenatal and child nutrition profiles were assessed among 65 and 329 children respectively by analyzing components of a food frequency questionnaire. Child neurodevelopmental outcomes at 4-6 years of age were measured using the McCarthy Scales of Children's Abilities (MSCA).

Interventions

OTHERNutrient mixtures

consumption of a mixture of beneficial nutrients

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 44 Years

Healthy volunteers

Inclusion criteria

Women of children: * less than 20 weeks gestation at the start of the study * at least 18 years of age * and planned to reside in Mexico City for the next three years.

Exclusion criteria

Women of children: * free of heart or kidney disease * not use steroids or anti-epilepsy drugs * not consume alcohol.

Design outcomes

Primary

Measure	Time frame	Description
McCarthy Scales of Children's Abilities (MSCA)	at age 4	The MSCA consists of 18 short sub-tests that are weighted and combined to yield five scale scores or indexes - verbal, perceptual performance, quantitative, memory and motor - as well as an overall general cognitive index based on the first three scaled indexes. The McCarthy Scale index scores can range from 22 - 78 with higher index scores indicating better outcome.

Countries

Mexico

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026