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Respiratory Mechanics in Intensive Care Patients

Study of the Respiratory Mechanics Characteristics With Esophageal PREssure Measurements in Mechanically Ventilated Patients in IntensivE caRe Unit

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03420417
Acronym
PREMIER
Enrollment
200
Registered
2018-02-05
Start date
2018-03-28
Completion date
2019-02-28
Last updated
2018-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intensive Care, Ventilator Lung

Keywords

Mechanical ventilation

Brief summary

This study aims at assessing the respiratory mechanics of intubated patients in intensive care unit.

Interventions

DEVICEEsophageal pressure measurement

Use of a nasogastric tube equipped with esophageal balloon to assess respiratory mechanics

Sponsors

University Hospital, Angers
Lead SponsorOTHER_GOV

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Age \> or = 18 years * Invasive mechanical ventilation on tracheal tube * Treatment with neuromuscular blocking agents * Nasogastric tube needed for enteral nutrition

Exclusion criteria

* Lack of free and informed consent * Pregnant or breastfeeding woman * Contra-indication to esophageal pressure measurement catheter

Design outcomes

Primary

MeasureTime frame
Chest wall compliance measurement (mL/cmH2O)1 hour

Secondary

MeasureTime frame
lung compliance measurement (mL/cmH2O)1 hour
End expiratory lung volume (mL)1 hour

Countries

France

Contacts

Primary ContactFrançois Beloncle, MCU-PH
Francois.Beloncle@chu-angers.fr0241353845

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 10, 2026