Gastric Cancer
Conditions
Keywords
cereal, whole grain, refined grain, gastric cancer, meta analysis
Brief summary
This project involved a systematic literature review of published trials of cereal or grain in relation to the risk of gastric cancer. Data was extracted from the publications on PubMed, EMBASE, Cochrane Library.A traditional meta-analysis, subgroup analysis, and heterogeneity was conducted on the extracted data.
Detailed description
Investigators searched PubMed, EMBASE, Cochrane Library for studies focusing on cereal or grain in relation to the risk of gastric cancer up to October 2017. Summary odd ratios (OR) and 95% confidence intervals (CI) were calculated by using either random effect models or fixed effect models according to the heterogeneity of included studies. Subgroup analysis, heterogeneity, and publication bias were also performed.
Interventions
DIETARY_SUPPLEMENTcereal or grain consumption
intake of cereal, whole grain, refined grain, and other grain of every day
Sponsors
West China Hospital
Study design
Observational model
OTHER
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
Yes
Inclusion criteria
* a case-control studies or a cohort study * investigate the association between cereal or grain intake and GC occurrence * report an odds ratio (OR) or relative risk (RR) with corresponding 95% confidence intervals (CI) * provide sufficient data to estimate OR or RR
Exclusion criteria
* Non-human studies * GC mortality-based cohort studies
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| the relationship between overall cereal consumption and gastric cancer occurance | up to 2 years | perform a pooled analysis of included studies with OR through STATA 12.0 |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| the relationship between whole grain and gastric cancer occurance | up to 2 years | perform a subgroup analysis to summarize the related OR through STATA 12.0 |
| the relationship between refined grain and gastric cancer occurance | up to 2 years | perform a subgroup analysis to summarize the related OR through STATA 12.0 |
| the relationship between other grain and gastric cancer occurance | up to 2 years | perform a subgroup analysis to summarize the related OR through STATA 12.0 |
Countries
China
Outcome results
None listed