Older HIV-infected Adults and Drug Interactions: French Cross-sectional Study

Older HIV-infected Adults and Drug Interactions: Nationwide Cross-sectional Study Based on French National Health Insurance Databases

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03416881

Acronym

POPVIH65

Enrollment

13225

Registered

2018-01-31

Start date

2016-01-01

Completion date

2016-12-31

Last updated

2018-01-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

HIV Infections

Keywords

HIV infection, antiretroviral, aging population, drug interactions, cross-sectional study, SNIIRAM

Brief summary

Drug interactions between antiretroviral drugs and concomitants drugs and between antiretroviral need to be studied HIV-population is ageing. The referential of interactions is the Liverpool base.

Detailed description

Filters in the French social security system database, 2016 : * Code of Pathology Human Immunodeficiency Virus (HIV) infection Age ≥ 65 years * Treatment with an antiretroviral between January 1, 2016 and December 31, 2016

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

66 Years to No maximum

Healthy volunteers

Inclusion criteria

* Men and women over than 65 years with an HIV infection and insured at the French Primary Health Insurance fund No

Design outcomes

Primary

Measure	Time frame	Description
frequency of major drug-drug interactions	between Jan, 1st 2016 and Dec, 31st 2016	MDDI between 2 drugs (ARV/ARV or ARV/non-ARV) delivered during the same period yielding to a Do Not Coadminister statement, according to the University of Liverpool website (www.hiv-druginteractions.org/checker).

Secondary

Measure	Time frame	Description
costs associated with major drug-drug interactions	during 2016	The costs were defined as all reimbursed healthcare acts recorded in the SNIIRAM

Outcome results