Social Behavior in Depression

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03414606

Acronym

HLGDep

Enrollment

Registered

2018-01-30

Start date

2017-02-01

Completion date

2018-03-01

Last updated

2018-02-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression

Brief summary

In the project, investigators basically plan to test the difference in social behavior and social cognition between depressive patients and healthy individuals. To test this, investigators plan to use traditional or novel behavioral experiment paradigms to target various behaviors.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

18 Years to 60 Years

Healthy volunteers

Yes

Inclusion criteria

* Age range between 18 and 60 * Education experience above high school * Score for Hamilton's Depression Scale \>=17 * Diagnosis of depression through Scid

Exclusion criteria

* Undergoing electric shock treatment in 3 months * Excluding those who with bipolar disorder * Excluding those who with postpartum depression * Excluding those who with hysteria

Design outcomes

Primary

Measure	Time frame	Description
Prosocial behavior	Baseline	The prosocial behavior will be assessed by conventional economic games, including dictator game, message game, and ultimatum game.
Cognitive flexibility	Baseline	Cognitive flexibility will be assessed by psychological cognitive paradigm, i.e. reversal learning paradigm. The participants will be asked to choose the item with high probability to win reward.
Valuation of social information	Baseline	The valuation of social information was measured by psychological paradigm, developed from animal studies, called pay-per-view. The participants will be asked make decision about more social information or more monetary reward.
Optimism bias	Baseline	Participants will complete two sessions of life event estimation, i.e. estimating their likelihood of experiencing each event on a self-paced basis.
Emotion recognition	Baseline	After viewing a video, participants will be asked to judge the person's attitude in the video. Through this paradigm, investigators could test emotional bias in social interaction in depressive patients.
Model-free & model-based tendency	Baseline	Participants will be asked to complete a two-stage task, by choosing the stimuli with high probability to obtain reward.

Countries

China

Contacts

Primary ContactYina Ma, Doctor

yma@bnu.edu.cn+8613810258647

Outcome results