Depression
Conditions
Brief summary
In the project, investigators plan to test difference of social cognition between depressive patients and healthy individuals and the brain activation underlying the difference to further understand the neural mechanism of depressive disorder.
Interventions
None listed
Sponsors
Huilongguan Hospital
Beijing Normal University
Study design
Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Inclusion criteria
* Age range between 18 and 60 * Education experience above high school * Score for Hamilton's Depression Scale \>=17 * Diagnosis of depression through Scid
Exclusion criteria
* Undergoing electric shock treatment in 3 months * Excluding those who with bipolar disorder * Excluding those who with postpartum depression * Excluding those who with hysteria
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| emotion recognition | Baseline | After viewing a video, participants will be asked to judge the person's attitude in the video. Through this paradigm, investigators could test emotional bias in social interaction in depressive patients. |
| resting state | Baseline | In this part, investigators basically want to test the automatic neural activity for depressive patients while they are resting. |
| self-reflection | Baseline | Participants will be asked to judge the discrepancy between actual self and ideal self. |
| response to negative stimuli | Baseline | investigators used face-matching task to measure their response to negative stimuli. The participants will be asked to detect the identical face with same emotion. |
| structure | Baseline | Investigators scanned structural images to detect the difference between clinical population and healthy population. |
| white matter | Baseline | Investigators scanned DTI to detect the difference between clinical population and healthy population. |
Countries
China
Contacts
Primary ContactYina Ma, Doctor
Outcome results
None listed