Preemptive Peripheral Nerve Block, Pain, Postoperative, Acute Pain
Conditions
Keywords
preemptive analgic effect, Rectus Sheath Block, laparoscopic cholecystectomy
Brief summary
The purpose of this study was to investigate the effectiveness of preemptive effect of rectus sheath block (RSB) and intercostal nerve block (ICNB) on postoperative visceral pain in laparoscopic cholecystectomy (LLC). After induction of general anesthesia, group of patient is decided randomly. In Group pre, RSB and ICNB are performed with 0.25% Ropivacaine 40ml before the operation. In Group post, RSB and ICNB are performed with 0.25% Ropivacaine 40ml after the operation. Measure the NRS and compare the rescue analgesic dose used at 0, 0.5, 1, 2, 6, 9, 18, and 24 hours after arrival at the recovery room.
Interventions
Ultrasound guided rectus sheath block with 0.25% ropivacaine 34ml around umbilicus
Ultrasound guided intercostal nerve block with 0.25% ropivacaine 6ml in 7,8,9 th intercostal space
Sponsors
Asan Medical Center
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
TRIPLE (Subject, Caregiver, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
20 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
1. adults between the ages of 20 and 80 2. scheduled laparoscopic cholecystectomy patient 3. ASA class 1 or 2 4. Patients who have voluntarily agreed in writing to participate in the trial
Exclusion criteria
1. Patient with side effects on local anesthetics or steroids 2. Patient who are taboo of peripheral nerve block such as blood clotting disorder, infection, etc. 3. Patients with uncontrolled medical or psychiatric problem 4. Patient does not agree to participate in the study 5. Patients who are pregnant or lactating 6. Patients whose visceral pain is expected to be too severe 7. Patients receiving a single laparoscopic cholecystectomy (including using a robot)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Difference of analgesic consumption between both group | at 0, 0.5, 1, 2, 6, 9, 18, 24 hours after operation | The difference in analgesics usage between the two groups after the operation is checked at fixed intervals (at 0, 0.5, 1, 2, 6, 9, 18, 24 hours after operation) to compare. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| compare the Numeric rating scale (NRS) | at 0, 0.5, 1, 2, 6, 9, 18, 24 hours after operation | The Numeric Rating Scale (NRS-11) is an 11-point scale for patient self-reporting of pain. It is for adults and children 10 years old or older. 0: No pain, 1-3: mild pain, 4-6: Moderate pain, 7-10: severe pain, 10: worst pain imaginable. After surgery, the NRS differences between the two groups were compared at a constant interval (0, 0.5, 1, 2, 6, 9, 18, 24 hours postoperatively). |
Countries
South Korea
Outcome results
None listed